Carotid Disease: The Role of Imaging in Diagnosis and Management

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Jonathan Gillard, Martin Graves, Thomas Hatsukami, Chun Yuan
Cambridge University Press, Dec 7, 2006 - Medical
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Stroke is a major cause of morbidity and mortality, with carotid disease representing an important contributory risk factor. This book is about the pathogenesis and management of carotid disease with specific focus on the role imaging has to play in the early recognition of symptomatic and asymptomatic disease as well as the treatment of the developed condition. Technological advances in imaging modalities now allow detailed analysis of the disease progression, the prediction of critical events leading to a stroke, as well as the identification of the most effective surgical or other interventional treatments. This book should be read by neurologists, cardiologists, vascular surgeons, neurosurgeons and radiologists involved in the care of patients with carotid disease, and also by researchers involved in the development of new therapeutic techniques and drugs.
 

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Contents

1
1
Epidemiology of carotid artery atherosclerosis
22
3
35
4
45
5
59
Surgical management of symptomatic
72
Surgery for asymptomatic carotid stenosis
86
Interventional management of carotid disease
94
Table 191 Overview of radiolabeled tracers for imaging of atheroscelorosis
255
Cerqueira et al 1992
256
USPIO enhanced magnetic resonance imaging
272
Gadoliniumenhanced plaque imaging
288
Carotid magnetic resonance direct thrombus imaging
302
23
313
Mechanical image analysis using finite element method1
324
25
341

9
105
Conventional digital subtraction angiography for
126
Magnetic resonance angiography
140
Computed tomographic angiography
158
Costeffectiveness analysis for carotid imaging
166
Figure 132 Example of use of Markov transition states to
170
MR plaque imaging
180
15
191
Assessment of carotid plaque with conventional
208
17
223
18
235
19
251
MR and CT perfusion
358
Near infrared spectroscopy in carotid endarterectomy
372
28
387
Monitoring carotid interventions with xenon CT
396
Table 291 cont
401
Figure 292 The response of several commonly measured variables to
406
Vascular imaging and the clinical development
418
Monitoring pharmaceutical interventions with
430
32
451
34
471
Future technical developments
484

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About the author (2006)

Jonathan Gillard is a Reader in Neuroradiology in the University of Cambridge, and an Honorary Consultant Neuroradiologist at Addenbrooke's Hospital.

Martin Graves is Consultant Clinical Scientist in the Departments of Radiology and Medical Physics at Cambridge University Hospitals NHS Foundation Trust.

Thomas Hatsukami is a Professor of Vascular Surgery at the University of Washington School of Medicine in Seattle, Washington.

Chun Yuan is a Professor of Radiology at the University of Washington, Seattle, Washington.

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