Case Studies of Existing Human Tissue Repositories: "Best Practices" for a Biospecimen Resource for the Genomic and Proteomic Era

Front Cover
Rand Corporation, Dec 19, 2003 - Medical - 246 pages
0 Reviews
Case studies of twelve existing human biospecimen repositories performed to evaluate their utility for genomics- and proteomics-based cancer research and to identify "best practices" in collection, processing, annotation, storage, privacy, ethical concerns, informed consent, business plans, operations, intellectual property rights, public relations, marketing, and education that would be useful in designing a national biospecimen network.
 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

CHAPTER ONE
1
National Dialogue on Cancer
3
RAND Study
5
Organization of This Report
6
CHAPTER TWO
7
Interviews
8
Repositories Evaluated
10
Repositories Not Included in the Evaluation
23
Industry Repositories
110
Repository Model
113
Costs
116
Developing and Adopting New Technologies
118
Tracking of Sample Use
119
Best Practices
120
CHAPTER SEVEN
121
Institutional Review Boards
126

Determining Best Practices
25
CHAPTER THREE
27
Biospecimen Processing and Annotation
44
Biospecimen Storage
59
Specimen Distribution
75
CHAPTER FOUR
84
Use of Bioinformatics Systems
85
Types of Data Contained in Bioinformatics Systems
90
Data Accessibility
91
Bioinformatics System Security
93
Quality Control Auditing and Standardization for Bioinformatics Systems
94
CHAPTER FIVE
96
Review and Prioritization of Requests for Tissue
101
Unmet User Needs
103
Tracking the Use of Biospecimens
104
Best Practices
106
CHAPTER SIX
108
Academic Repositories
109
Consent Issues
132
Best Practices
135
CHAPTER EIGHT
138
Rights of Tissue Source and Contributing Institutions to Tissue
140
Compensation
141
Agreements Used in Tissue Distribution
142
Liability Issues
143
Best Practices
144
CHAPTER NINE
146
Outreach Patient Education and PostResearch Communications
147
Best Practices
148
CHAPTER TEN
149
Best Practices
168
Conclusions
191
APPENDIX Interview Instrument for RAND Evaluation of Existing Tissue Resources
193
Glossary
203
References
207
Copyright

Other editions - View all

Common terms and phrases

Bibliographic information