Casting Type Calcifications: Sign of a Subtype with Deceptive Features: Sign of a Subtype with Deceptive Features

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Thieme, Jan 1, 2011 - Medical - 325 pages
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This book is dedicated to those physicians who believe that greater knowledge of the many subtypes of breast cancer will lead to more individualized diagnosis and therapy, to the ultimate benefit of their patients.--the authorsIn Breast Cancer: The Art and Science of Early Detection with Mammography-Perception, Interpretation, Histopathologic Correlation, Lszl Tabr, one of the worlds most renowned mammographers, has shared his decades of experience in presenting the fundamentals of perception and interpretation of mammographic images. This is the second volume in a series of books written by the team of Tabr, Tot, and Dean describing breast cancer in its earliest phase according to the imaging findings and correlating these findings with sophisticated histopathologic images and patient outcome. This volume covers a particularly troublesome subtype of breast cancer characterized by casting type calcifications.Highlights:- Extensive coverage of the morphology and outcome of this deceptive breast cancer subtype- Nearly 1000 illustrations of stunning quality showing the full range of manifestations- Photomicrographs of large, thin-section pathology slides and unique 3D pathology images which are carefully correlated with mammographic images to explain why mammograms appear as they do- Stereoscopic images that demonstrate normal breast structures and the distortion caused by this unique malignant process- Presentation of an original theory of neoductgenesis to explain the surprising disease outcome all too frequently observed- Scientific rationale for using individualized treatment methods which include the mammographic prognostic featuresFurther volumes in the series will cover- Crushed stone--like and powdery calcifications- Spiculated lesions and architectural distortionLszl Tabr, MD, is Professor of Radiology at Uppsala University and Head of the Department of Mammography at Falun Central Hospital in Falun, Sweden.Tibor Tot, MD, is Associate Professor of Pathology at Uppsala University and Chairman of the Department of Pathology and Clinical Cytology at Falun Central Hospital in Falun, Sweden.Peter B. Dean, MD, is Professor at the Department of Diagnostic Radiology at the University of Turku in Turku, Finland, and formerly Visiting Professor at Brigham and Womens Hospital, Harvard Medical School, Boston, MA, USA.
 

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Contents

General Introduction 3 Characteristic Mammographic and Histological
16
Anatomical Background 4 MammographicHistological Correlation When
25
Cluster of Calcifications as the Earliest Sign
80
No Apparent Abnormality on the Previous Subtle Casting Type Calcifications as the Earliest
118
The Theory of Neoductgenesis
127
C Disorganized Architecture
138
Morphological Demonstration of Neoductgenesis 135 E Tenascin Overexpression
154
Poor Correlation of Outcome with Mode of Therapy
204
Recognition of the Unpredictable Often Fatal Nature of the Breast Cancer
227
Distant Metastases with Casting Type Calcifications
266
Illustrative Cases with 3Dimensional Stereoscopic Histological Images
273
3 283 Case 6 7 300
283
References
309
Demonstration of Fatal Cases with Casting Type
311
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About the author (2011)

Professor of Radiology, University of Uppsala School of Medicine, and Director, Dept. of Mammography, Central Hospital, Falun, Sweden

Associate Professor of Pathology, University of Uppsala School of Medicine, and Chairman, Dept. of Pathology and Clinical Cytology, Central Hospital, Falun, Sweden

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