Catalysis in Chemistry and Enzymology

Front Cover
Courier Corporation, Jan 1, 1987 - Science - 836 pages
Exceptionally clear, carefully written treatment of the nature of catalysis of reactions in aqueous solution. Coverage of mechanisms for catalysis, forces in aqueous solution, carbonyl- and acyl-group reactions, practical kinetics, and much more. Extensive bibliography. "... a masterpiece."—Nature.
 

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language is tougher and not east to nderstand and their are a lot of contradictions.

Contents

Observation of the formation and disappearance of
1
MECHANISMS FOR CATALYSIS
4
Covalent Catalysis
42
intermediate
45
Decomposition at the same rate of a common intermediate formed from different substrates
50
Partitioning of the intermediate to give two products at a constant total rate
53
Partitioning of a common intermediate to a constant ratio of two products
56
Exchange and transfer reactions
60
ATP and metals
112
Decarboxylation of Bketo acids 1 16
116
Aldol condensations
120
Thiamine pyrophosphate
127
Pyridoxal
133
Other examples
146
F Oxidative Catalysis
150
G Oxidative Activation
154

Exchange and inhibition
64
Nucleophilic Catalysis
67
Nucleophilic groups in enzymes
71
Carbonyl transfer reactions
72
cistrans Isomerization
74
Phosphate transfer
76
Alkyl transfer
77
Nucleophilic Reactivity
78
Basicity
79
Polarizability oxidationreduction potential softness
85
Solvation
92
Steric hindrance
96
Electrostatic effects
97
Resonance stabilization and structural rearrangements
98
Bond strength to carbon
99
Intramolecular general acid catalysis
103
The a effect
107
E Electrophilic Catalysis
111
General AcidBase Catalysis
163
Other examples
168
B The Brønsted Relationship
170
Isotope Effects
243
Strain Distortion and Conformation Change
282
FORCES IN AQUEOUS SOLUTION
321
Electrostatic Interactions
351
Hydrophobic Forces
393
DonorAcceptor and Charge Transfer Interactions
437
PART III
460
RCSR and HOR
517
12
548
Practical Kinetics
555
Summary of rules for intepretation
612
Name Index
807
Subject Index
823
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