Catalysis in Chemistry and Enzymology

William P. Jencks

Courier Corporation, 1987 - Science - 836 pages

Exceptionally clear, carefully written treatment of the nature of catalysis of reactions in aqueous solution. Coverage of mechanisms for catalysis, forces in aqueous solution, carbonyl- and acyl-group reactions, practical kinetics, and much more. Extensive bibliography. "... a masterpiece."—Nature.

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User Review -

language is tougher and not east to nderstand and their are a lot of contradictions.

Contents

• Obseriation of the formation and disappearance of: 1
• MECHANISMS FOR CATALYSIS: 8
• Chapter: 9
• Covalent Catalysis: 42
• intermediate: 45
• Decomposition at the same rate of a common intermediate farmed from different substrates: 50
• Partitioning of the intermediate to give two products at a constant total rate: 53
• Partitioning of a common intermediate to a constant ratio of two products 5 6: 56
• Exchange and transfer reactions: 60
• Exchange and inhibition: 64
• Nucleophilic Catalysis: 67
• Nucleophilic groups in enzymes: 71
• Carbonyl transfer reactions: 72
• cistrans Isomerization: 74
• Phosphate transfer: 76
• AUtyl transfer: 77
• Nucleophilic Reactivity: 78
• Basicity: 79
• Polarizability oxidationreduction potential softness: 85
• Solvati: 92
• Steric hindrance: 96
• Electrostatic effects: 97
• Resonance stabilization and structural rearrangements: 98
• Bond strength to carbon: 99
• Intramolecalar general acid catalysis 1 03: 104
• The a effect: 107
• E Electrophilic Catalysis 11 1: 111
• ATP and metals: 112
• Decarboxylation of pketo acids: 116
• Aldol condensations: 120
• Thiamine pyrophosphate: 128
• Pyridoxal: 133
• Other examples: 146
• F Oxidative Catalysis 1 50: 154
• General AcidBase Catalysis 1 63: 163
• Other examples: 168
• B The Boosted Relationship: 170
• Isotope Effects: 243
• Strain Distortion and Conformation Change: 282
• FORCES IN AQUEOUS SOLUTION: 321
• Electrostatic Interactions: 351
• Hydrophobic Forces: 393
• DonorAcceptor and Charge Transfer Interactions: 438
• Related Phenomena and Long Electrondeficient Bonds: 449
• Charge Transfer and DonorAcceptor Interactions in Biochemistry: 459
• RCORandHOR: 508
• RCSRand HOR: 517
• RCSRandHzNR: 537
• 1: 553
• B The Utilization of Pseudo Firstorder Rate Constants: 568
• APPENDIX: 615
• Name Index: 807
• Subject Index: 823

Bibliographic information

• Title: Catalysis in Chemistry and Enzymology; Dover books on physics and chemistry; McGraw-Hill series in advanced chemistry
• Author: William P. Jencks
• Edition: illustrated, reprint, revised
• Publisher: Courier Corporation, 1987
• ISBN: 0486654605, 9780486654607
• Length: 836 pages
• Subjects: Science / Chemistry / General