Cell Lineage and Fate Determination
Sally A. Moody
Elsevier, Oct 29, 1998 - Science - 644 pages
Cell Lineage and Fate Determination provides a comprehensive view of the mechanisms regulating cell lineage and fate determination in an effort to understand how the fertilized egg is transformed into a complex of specialized tissues. It presents basic information on eight different animal models and recent developmental biological research done in each model. The book provides a focused forum presenting key information for researchers studying various aspects of developmental and cellular biology. Extensive use of tables and black-and-white and color figures helps illustrate each model. The book concludes by discussing future goals for bringing cellular, molecular, and genetic research to clinical applications and tissue replacement therapies.
* Presents eight different animal models
* Provides a focused forum on cell fate determination that provides comprehensive and key information for researchers
* Illustrates the transitional relationship between researchers and clinicians
* Includes the extensive use of tables and color figures
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activin activity animal ascidian axis Biol blast cell blastomeres blastula bryos Caenorhabditis elegans cardiac Cell Cambridge cell cycle cell division cell fate cell lineage cell types cleavage clones cortex cortical cytoplasmic deﬁned Development Cambridge developmental differentiation domain dorsal Drosophila early ectoderm ectopic embryo embryogenesis encodes endoderm epiblast epidermis explants fate map ﬁrst formation function gastrulation gene expression genetic germ cells germ layers homeobox homolog Horvitz identiﬁed induction interactions kinase leech markers maternal ment mesenchyme mesoderm micromeres molecular morphogenetic mRNA muscle mutant mutant embryos Nature London neural crest neural plate neuroblast neurons normal notochord oocytes organizer phenotype polarity posterior primitive streak progenitors protein receptor region regulation retina role sea urchin sea urchin embryo segmental siamois somite speciﬁcation stage studies suggest tail bud teloblasts tion tissue transcription factor vegetal ventral vertebrate vulval Weisblat Wg signaling Xenopus embryos yolk zebraﬁsh zygotic