Cell Surface and Extracellular Glycoconjugates: Structure and Function

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Academic Press, Dec 2, 2012 - Science - 314 pages
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This book serves as a much-needed guide for new investigators in the field of glycobiology as well as researchers in other disciplines attempting to define the role of glycoconjugates in their biological systems. Cell Surface and Extracellular Glycoconjugates: Structure and Function describes the determination of structure and function of glycoconjugates that occur on the cell surface and in molecules involved in cell-matrix interactions. The broad scope of thebook covers basic background and technical information in this rapidly expanding field. The text is specifically designed to inform researchers in diverse disciplines of the approaches and resources that can be employed to address problems in glycoconjugate biology.


Includes coverage of the:

* Structure of cell surface carbohydrates
* Biosynthesis of glycoproteins
* Biological signals associated with glycoproteins
* Diversity of glycoprotein structure
 

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Contents

Chapter 1 Use of Structural Analyses to Examine the Functions of N and OLinked Sugar Chains of Glycoproteins
1
Chapter 2 Structure and Biology of Pericellular Proteoglycans
33
Structure Biosynthesis and Function
83
Chapter 4 The Use of Glycosylation Inhibitors to Study Glycoconjugate Function
119
Chapter 5 Use of Mammalian Cell Mutants to Study the Functions of N and OLinked Glycosylation
181
Chapter 6 The Structure and Function of Glycosphingolipid Receptors in Inflammation and Cancer
223
Analysis of Glycosylation Function in Human Choriogonadotropin
245
Chapter 8 The Role of Glycosylation in Adhesive Protein Function
271
INDEX
309
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