Cell Cycle Inhibitors in Cancer Therapy: Current Strategies

Antonio Giordano, Kenneth J. Soprano

Humana Press, 2003 - Medical - 326 pages

Leading clinicians and investigators review in a comprehensible and user-friendly style all the latest information about the molecular biology of cell cycle control and demonstrate its clinical relevance to understanding neoplastic diseases. Topics range from Cdk inhibitors and cell cycle regulators to the prognostic value of p27 and tumor suppressor genes as diagnostic tools. Actual case studies show how the new molecular understanding has produced such drugs as Flavopiridol and Sulindac. The book brings all the recent critical research findings to bear on clinical practice, and clearly shows their powerful impact on the diagnostics, prognostics, and therapeutics of cancer, AIDS, and cardiovascular disease.

About the author

Mahi Binebine was born in Marrakech in 1959. He studied in Paris and taught mathematics, until he became recognized first as a painter, then as a novelist. Binebine lived in New York in the late 1990s, when his paintings began to be acquired by the Guggenheim Museum. His first novel, Welcome to Paradise was published in France by Librairie Artheme Fayard in 1999, in Great Britain in 2003 by Granta Books, and in the Unites States in 2012 by Tin House Books. He lives in Marrakech.

Lulu Norman is a writer, translator, and editor who lives in London. She has translated Albert Cossery, Mahmoud Darwish, Tahar Ben Jelloun, and the songs of Serge Gainsbourg and written for national newspapers, the London Review of Books, and other literary journals. Her translation of Mahi Binebine's Welcome to Paradise (Granta, 2003; Tin House Books, 2012) was shortlisted for the Independent Foreign Fiction Prize. She also works as assistant editor of Banipal, the magazine of modern Arab literature.

Bibliographic information

• Title: Cell Cycle Inhibitors in Cancer Therapy: Current Strategies; Cancer Drug Discovery and Development
• Editors: Antonio Giordano, Kenneth J. Soprano
• Edition: illustrated
• Publisher: Humana Press, 2003
• ISBN: 0896039307, 9780896039308
• Length: 326 pages
• Subjects: Medical / Clinical Medicine; Medical / Oncology / General; Medical / Pharmacology; Medical / Pharmacy