Cellular Aspects of Smooth Muscle Function
C. Y. Kao, Mary E. Carsten
Cambridge University Press, Aug 28, 1997 - Medical - 293 pages
Smooth muscles line many internal organs and, in general, are involved in moving fluids and slurry around the body. They are controlled by the action of hormones, by nervous stimulation, and can be influenced by drugs. This 1997 book provides a review of our understanding of smooth muscle and integrates molecular, cellular and physiological information with tissue and anatomical studies. Well-known researchers have written chapters giving detailed reviews of our current knowledge of the biochemistry, pharmacology, physiology and anatomy of smooth muscle. In particular, they cover the seven most important areas of smooth muscle function including morphology, electrophysiology, mechanisms of electromechanical and pharmacomechanical coupling, calcium homeostasis, signal transduction, mechanics of contraction, and the contractile proteins. All those interested in muscular contraction will find this book worthwhile, whether they are biochemists, physiologists, or cell biologists.
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acid actin actin filaments action potential affinity agonists artery ATPase ATPase activity binding Biochem Biophys Bolton Ca,Mg-ATPase Ca”-activated calcium caldesmon calmodulin calponin canine cation current caveolae cellular Chalovich Chem cholinergic concentration crossbridges cytoplasm cytoskeleton dense bodies depolarization effect enzyme fibers Figure force function G proteins Gabella guinea-pig half-maximal heavy chain inactivation increase inhibition inositol Inoue InsP3 intestine intracellular Isenberg isoforms isolated isometric isotonic Kamm length light chain kinase Lond mechanical Meiss MLCK motility muscarinic myocytes myofilaments myometrium myosin light chain nonselective cation outward current permeabilized Pharmacol phosphatase phosphorylation Physiol physiological properties protein kinase rabbit receptor regulation regulatory relaxation release RLC phosphorylation role sarcoplasmic reticulum shortening Sims skeletal muscle smooth mus smooth muscle cells smooth muscle contraction smooth muscle myosin smooth myocytes Somlyo stiffness stimulation structure studies Stull subunit thin filaments tissue tracheal smooth muscle tropomyosin uterine myocytes vascular smooth muscle vitro voltage Wang Warshaw