Cellular Signaling and Innate Immune Responses to RNA Virus Infections

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Allan R. Brasier, Adolfo García-Sastre, Stanley M. Lemon
ASM Press, 2009 - Medical - 436 pages
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A comprehensive survey of the most recent discoveries in this field.

  • Provides a platform of knowledge that will lead to the development of more effective methods for controlling the spread of RNA viruses or modifying their disease course.
  • Synthesizes recent findings in this fast-moving field while also reviewing accepted knowledge.
  • Focuses on the antiviral signaling pathways in the host, including specific pattern recognition receptors and how these cellular alarms signal the innate immune response.
  • Examines the ways in which specific major RNA virus families interact with, activate, and elude these signaling pathways and responses.

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