Cellular Signaling and Innate Immune Responses to RNA Virus Infections
A comprehensive survey of the most recent discoveries in this field. Provides a platform of knowledge that will lead to the development of more effective methods for controlling the spread of RNA viruses or modifying their disease course. Synthesizes recent findings in this fast-moving field while also reviewing accepted knowledge. Focuses on the antiviral signaling pathways in the host, including specific pattern recognition receptors and how these cellular alarms signal the innate immune response. Examines the ways in which specific major RNA virus families interact with, activate, and elude these signaling pathways and responses.