Cellular Aspects of HIV Infection
Andrea Cossarizza, David Kaplan
Wiley, 2002 - Medical - 458 pages
Cellular Aspects of HIV Infection provides a highly readable, detailed overview of the state of the art in modern HIV research at the cellular level. This volume brings together renowned experts who have provided concise, synthetic treatments of the biology of HIV infection. It presents these descriptions and analyses with particular attention to the techniques of flow cytometry that have allowed us to not only observe the course of HIV infection and the immune system's response to it, but have also increased our ability to treat patients and understand their response to therapy.
The book is divided into five sections covering molecules and cells, pathophysiological processes, technologies, and organisms. A perspective on future therapies concludes the book. Each chapter offers an intelligent, concise synthesis of the topic, highlighting the biological principles and technologies involved in the study of HIV infection. Cellular Aspects of HIV Infection is an indispensable, up-to-date guide for immunologists, virologists, clinicians, and researchers.
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HIV and Molecular Biology of the VirusHost Interplay
Telomere Length CD28 T Cells and HIV Disease Pathogenesis
Immune Dysregulation and TCell Activation Antigens
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Acad Sci USA activation ADCC alveolar macrophages analysis antibodies antigen antigen-specific antiretroviral therapy antiviral apoptosis binding Biol CCR5 CD4 cell CD4 T cells CD4+ CD8+ cell receptor cellular chemokine receptor Clin coreceptor correlated Cossarizza CXCR4 cytokines cytotoxic T lymphocytes DC-SIGN delta T cells dendritic cells detected disease progression effector epitopes factor flow cytometry fluorescent function gamma delta gene HAART HIV disease HIV infection HIV replication HIV-infected individuals human immunodeficiency virus IFN-y immune response immunodeficiency virus type Immunol increase induced infected cells inhibition interactions interleukin intracellular levels ligand lymphoid macrophages markers mediated membrane memory T cells mice mitochondrial molecules monocytes naive Natl Acad Sci NK cells pathogenesis pathogens patients PBMC peripheral blood phenotype primary Proc Natl Acad production protein repertoire role specific studies subset target cells telomere tissues TNF-a tumor viral load viral replication virions Virol vitro vivo Völ yö T cells