Cellules Hépatiques Et Médicaments
John Libbey Eurotext, 1988 - Gastrointestinal agents - 494 pages
This book contains the 17 lectures given at the International Symposium on Liver Cells and Drugs held in Rennes on 7 to 10 July 1987 as well as 50 communications presented at the poster sessions.
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J P Benhamou
O F W James M D Rawlins H Wynne K W Woodhouse
F P Guengerich D R Umbenhauer C Ged T Muto R W Bork
T Cresteil H J Eisen
P I Mackenzie S J Haque
acetaminophen acid activity albumin amineptine animals antibodies antigens assay bile Biochem Biol biotransformation buffer caffeine calcium carbamazepine cDNA cell line Cells and Drugs cellular Chem chemical Clin Colloque INSERMJohn Libbey compounds concentration conjugation covalent binding culture medium cultured hepatocytes cytochrome P-450 cytotoxicity decreased dose drug metabolism drug-induced effect enzymes epoxide epoxide hydrolase erythromycin ethanol glucuronide glutathione GSH transferases Guengerich Guguen-Guillouzo Guillouzo halothane halothane hepatitis hepatocyte cultures hepatocytes hepatoma hepatoma cells hepatotoxicity HPLC human hepatocytes human liver increased incubation induced inhibition INSERM INSERMJohn Libbey Eurotext intracellular isolated hepatocytes isozymes Larrey Libbey Eurotext Ltd lipid liver Liver Cells liver microsomes médicaments membrane metabolites microsomes monooxygenase mRNA oxidation paracetamol pathways patients perfusion Pessayre Pharmacol phenobarbital plasma primary culture prolidase protein rabbit rat liver Ratanasavanh reaction reactive metabolites serum specific studies substrate subunit synthesis tienilic acid toxicity treatment valproate vitamin vitro vivo xenobiotics
Page 470 - Chirgwin, JM, Przybyla, AE, MacDonald, RJ, and Rutter, WJ (1979) Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18, 5294-5299.