Cerebral Ischemia and Resuscitation
This fascinating monograph is filled with information formerly found only in periodicals and symposia proceedings. Chapters discuss the different models of cerebral ischemia in use today, including their advantages and disadvantages. This one-of-a-kind resource also contains essential chapters on cellular mechanisms of ion and acid-base homeostases, and energy metabolism of the ischemic brain. It reviews the possible role of lipids, free fatty acids, and free radicals. Four chapters are devoted to neurotransmitters and neuroregulators in cerebral ischemia. This extraordinary work also covers aspects of protection against and resuscitation from cerebral ischemia. An extremely informative volume, this book is an absolute must for every student in the field of cerebral ischemia, as well as the clinician or scientist who is already involved with this worldwide problem.
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TABLE OF CONTENTS
A Stroke Model Designed for Preclinical Trials
Immunohistochemical Assessment of Cerebral Ischemia
Monitoring of Cerebral Ischemia
accumulation acidosis Acta activity adenosine animals anoxia arachidonic arachidonic acid astrocytes biochemical Blood Flow Metab brain damage brain ischemia Brain Res brain tissue calcium calcium antagonists carotid artery cell death cellular cerebral blood flow cerebral cortex cerebral infarction cerebral ischemia changes complete ischemia concentration cortical creatine cytosolic decrease depletion depolarization drugs effect energy metabolism enzymes experimental Figure flunarizine focal forebrain ischemia free radical function gerbil glial glucose glutamate hippocampal slices homeostasis hyperglycemia hypoxia hypoxic increase induced inhibition injury intracellular ischemic ischemic brain ischemic insult kinase Klatzo lactate levels mechanisms membrane metabolism metabolites mitochondrial Mrsulja nerve cell Neurochem neurological neuronal neuronal damage Neuropathol Neurosci neurotransmitters NMDA receptors normal oxidative oxygen perfusion phosphate phospholipase phosphorylation Physiol postischemic postsynaptic potential presynaptic protein Pulsinelli purine pyramidal cells rat brain recirculation recovery reduced regions release reperfusion respiration Siesjö Stroke studies synaptic transmission transient vascular vitro vivo