Chemical mutagens: principles and methods for their detection

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Plenum Press, 1978 - Medical - 364 pages
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Analysis of body fluids including alkylation of macromolecules for detection of mutagenic agents; Use of yeast as an assay system for industrial mutagens; Heritable-translocation test in mice; Detection of mutation damage in ferm populations: an in situ bioassay for mutagens in aquatic ecosystems; The discovery of human teratogens, carcinogens, and mutagens: lessons for the future; Analysis of chromosome aberrations in mammalian germ cells; The mammalian spot test: a sensitive in vivio method for the detection of genetic alterations in somatic cells of mice; Dosimetry of chemical mutagens in eukaryote germ cells; Chick embryos for detecting environmental mutagens; Specific-locus mutations in mice; The induction of sperm-shape abnormalities in mice and humans.

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Methods in Cell Biology, Volume 6

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