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Chirality in IndustryAn Overview
Resolution of Racemates by Diastereomeric Salt Formation
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A. N. Collins acetate acylase alcohol aldehyde amidase amino acid amide amino acids aminotransferase application aspartame asymmetric synthesis asymmetric transformation BINAP biocatalyst biological bioreactor Boesten carbon carboxylic acids catalysts cells Chapter Chem chemical chiral amine cofactor commercial complex compounds concentration conversion COOH corallina B-276 crystallization cyanohydrins derivatives developed diastereoisomer diastereomeric ds-dihydrodiols enantiomer enantiomeric excess enantiomerically pure enantioselectivity enzyme epoxides ester example Figure G. N. Sheldrake glucose glycidyl ether hydrogenation hydrolysis hydroxycarboxylic hydroxyisobutyric acid immobilized industrial intermediate isobutyric acid isolated isomer ketones kinetic resolution L-amino L-aspartic acid L-phenylalanine lactone materials membrane menthol methanol method microbial microorganisms mixture mutant naproxen obtained OH OH olefins optical purity optically active optically pure organic oxide peptide pharmaceuticals phospholipids prochiral production Pseudomonas putida racemase racemic reaction reactor recycle reduction resolving agent route rugosa Scheme selectivity solution solvent stereochemistry stereoselective strain substrate specificity synthetic Table Tetrahedron Lett yield