Cholecystokinin and Its Antagonists in Pain Management
Examine the strong evidence of this unrealized pain management tool
Cholecystokinin (CCK), the regulatory peptide hormone found primarily in the gastrointestinal tract that works as a neurotransmitter throughout the nervous system, has been researched for years. CCK antagonists in conjunction with opioids are beginning to be seen as having possible major therapeutic benefits in pain management. Cholecystokinin and Its Antagonists in Pain Management is an extensive examination that gathers the mounting compelling evidence into one comprehensive source. Here researchers, neuroscientists, physicians, and pharmacy professionals are given the research and findings they need to explore the possible applications of CCK antagonists for a variety of illnesses.
Cholecystokinin and Its Antagonists in Pain Management extensively describes opioids in pain management, CCK and the body’s uses for the chemical, CCK receptor antagonists, and the evidence that points to its being a possible breakthrough application in pain management. Various animal studies are offered that present a convincing view of what may be the future of chronic pain management, with less side effects and a reduction in analgesic tolerance than when opioids are used alone. Potential uses of CCK antagonists are clearly discussed. The book is comprehensively referenced and provides several tables and graphs to fully illustrate the research findings.
Topics in Cholecystokinin and Its Antagonists in Pain Management include:
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Cholecystokinin As a Gut Peptide
Central Effect of Cholecystokinin
Cholecystokinin As an Antiopioid Peptide
Cholecystokinin Receptor Antagonists
Do Cholecystokinin Antagonists Influence
Comparisons Between CCK Antagonists
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acid acute affinity agonist alfentanil allodynia analgesic analgesic effect analgesic tolerance Anesth Analg animals antagonism Antagonists in Pain antinociceptive effect antinociceptive tolerance anxiolytic axotomy Brain Res caerulein CCK antagonists CCK levels CCK mRNA CCK-B CCK-like immunoreactivity CCKA CCKB receptor cells cholecystokinin octapeptide cholecystokinin receptor chronic pain Clin clinical colleagues delta opioid devazepide dihydrocodeine dorsal horn dose of morphine Dourish CT effect of CCK effect of morphine enhanced enkephalin fect fentanyl gallbladder gallbladder contraction Haworth Press human hyperalgesia increase induced inhibition injection intrathecal intravenous loxiglumide McCleane mice morphine analgesia morphine antinociception morphine tolerance morphine-induced mRNA naloxone neurones neuropathic pain Neurosci nociceptive nucleus opioid receptors opioid-derived oxycodone Pain Management pain relief pain scores pancreatitis patients peptide periaqueductal gray peripheral Pharmacol Exp Ther phine placebo plasma potentiation pretreatment produced proglumide receptor antagonist Roques BP side effects spinal cord strong opioids tail-flick tramadol transdermal fentanyl treatment Wiesenfeld-Hallin withdrawal