Circadian Clocks and Their Adjustment

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John Wiley & Sons, Apr 30, 2008 - Science - 348 pages
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Prestigious contributors describe the genetic, molecular, anatomical and neurochemical mechanisms and pathways that operate to regulate and control circadian rhythmicity and functioning in organisms ranging from unicellular algae to human beings. Also considers the implications of the basic and clinical research for humans.
 

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Contents

lntrod uction
1
The genetic basis of the circadian clock identification of frq and FRQ as clock components in Neurospora
3
The effects of temperature change on the circadian clock of Neurospora
26
Cellular analysis of a molluscan retinal biological clock
51
Circadian pacemakers in vertebrates
67
Organization of the mammalian circadian system
88
General discussion l
107
The effects of light on the Gonyaulax circadian system
117
Immediateearly genes and the neural bases of photic and nonphotic entrainment
175
Interaction between the circadian clocks of mother and fetus
198
Alterations in the circadian system in advanced age
212
Clinical chronopharmacology the importance of time in drug treatment
235
The effect of light on the human circadian pacemaker
254
Melatonin marks circadian phase position and resets the endogenous circadian pacemaker in humans
303
General discussion II
322
Index of contributors
327

Intrinsic neuronal rhythms in the suprachiasmatic nuclei and their adj ust men t
134
A nonphotic gateway to the circadian clock of hamsters
154

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