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EFFECTS OF BEDREST ON CIRCADIAN RHYTHMICITY
CHANGES IN GLUCOSE INSULIN AND GROWTH HORMONE
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42 DAYS 48-hr sampling period 54 of bedrest 56 days 56-DAY BEDREST STUDIES ambulatory and bedrested ambulatory controls ambulatory subjects area represents lights-off associated with bedrest BEDREST DAY 76 bedrest on circadian bedrest results bedrested subjects body temperature cardiotachometer catecholamine circadian rhythms circadian synchrony circulating levels confinement corticosteroid cortisol levels DAYS BED REST days of bedrest decreased desynchronization diurnal rhythms effect of bedrest effects of prolonged endocrine endocrine and metabolic environment excretion EXER-GENIE five subjects glucose levels growth hormone heart rate homeostasis hydrocortisone hypoglycemia integrated amplitude Integrated daily mean mean circulating mean daily NONEXERCISED ORCADIAN parameters parathormone levels peak PERIODOGRAMS phase angle phase shift photoperiod pituitary-adrenal Plasma ACTH Plasma cortisol Plasma parathormone postbedrest period prebedrest prolonged bedrest reported represents lights-off period rhythm asynchrony rhythmicity schedule serum stipled area represents subjects showed summation dial thyroid hormone thyroxine triiodothyronine urinary vector vertical lines represent Winget