Clinical Trials in Rheumatology
Springer Science & Business Media, Dec 1, 2010 - Medical - 771 pages
A huge number of therapeutic studies has been published in rheumatology and clinical immunology. This number grows substantially by the year. As such, it becomes increasingly difficult to keep track of this multitude of studies and the ensuing therapeutic trends. Further to this, a particular study can be referred to in a variety of ways, either as a shortened version of the title or an acronym, adding to the confusion. The book Clinical Trials in Rheumatology provides a summary of the important studies in the field for easy reference. Every study is shown with name, acronym (if in existence), authors, complete citation, study design, results, and summary. An acronym finder is supplied at the beginning of the book. This book is a valuable reference tool for rheumatologists and other clinical specialties, as well as for research scientists interested in immunomodulatory and selected other drug therapies in rheumatologic diseases.
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ANCAAssociated Vasculitis Churg Strauss syndrome Polyarteritis Nodosa and other vasculitic entities
Purpura Schoenlein Henoch
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100 mg Golimumab abatacept ACR 20 ACR Adalimumab ambrisentan anakinra anakinra 30 ankylosing spondylitis Arthritis Rheum Authors Publication Follow azathioprine bosentan ciclosporin clinical comorbidity Concomitant medication corticosteroids cyclophosphamide disease activity Disease duration DMARDs double-blind Epub Etanercept Follow up ACR Follow up Note Golimumab Hydroxychloroquine Hypertension iloprost Infliximab joints ³ Leflunomide low dose lupus methotrexate methylprednisolone mg ambrisentan mg Gol mg MTX/week mg/day mg/dL mg/kg Toc mg/kg/day mg/L mg/week monotherapy Morning stiffness Nausea Note Adverse events NSAIDs NSAIDs were permitted oral pain Patient’s global assessment Patients Authors Publication patients with active placebo prednisolone prednisone Previous medication psoriatic arthritis RA patients randomized relapse remission Result Patients Authors rheumatoid arthritis Rituximab score stable doses steroids Substance Result Patients Sulfasalazine Swollen joint count syndrome tacrolimus Tapered Tender joint count tocilizumab treatment Trial Substance Result vasculitis