Clinical Epidemiology: The Essentials
Williams & Wilkins, 1996 - Medical - 276 pages
This text introduces the student to epidemiology, providing a guide through questions and answers surrounding the dynamics of well-planned and interpreted research, grant reviews and critical appraisal. This edition includes information on AIDS, helicobacterpylori infection, breast and colon cancer screening, and gastric and peptic ulcers. Research aimed at answering questions such as diagnosis, prognosis and treatment is examined, and the text also looks at how the results of such research can be protected from distortion by bias and chance. Each chapter contains a summary and suggested readings.
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abnormal analysis Ann Intern assessment associated bias biased biologic blood pressure case-control studies cause cervical cancer chance Chapter characteristics clinical epidemiology clinical questions clinical trials clinicians cohort studies colorectal cancer compared comparison confidence interval considered control group criteria curve death described detect diagnostic tests drug Engl error estimate evaluation evidence examination example exposure false-positive Figure follow-up frequency hospital hypertension hypothesis incidence increased intervention JAMA large number likelihood ratios lung cancer measurements medical literature medicine methods mortality myocardial infarction negative normal NSAIDs number of patients observed occur odds ratio outcome events particular physicians placebo population positive predictive value possible prevention prognosis prostate prostate cancer random variation randomized controlled trial randomized trials relationship relative risk renal reports risk factors Sackett DL sample screening test selected sensitivity and specificity serum sigmoidoscopy smoking statistical power survival symptoms test result therapy tion treated treatment effects usually validity variables