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Signal Transduction in Unicellular Eukaryotes
The Role of G Proteins in Yeast Signal Transduction K Matsumoto M Nakafuku
Analysis of the Role of SCG1 a Ga Homolog and SST2 in Pheromone Response
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a-factor Acad adenylate cyclase alíele amino acid analysis antibodies assay binding Biochem Biol bombesin c-fos c-jun cAMP carboxy-terminal cDNA cellular ceptor Chem cloned Cold Spring Harbor coli complex containing cytoplasmic Dictyostelium DNA-binding domain effector element encodes enzyme extracts fibroblasts Figure fragment function fusion G proteins GCN4 gene product genetic glucocorticoid growth factor GTP-binding guanylate cyclase homologous hormone indicated induced inhibition inositol insulin interaction intracellular lane levels ligand lipid mammalian mating mediated molecular molecules mRNA mutants Nati nuclear nucleotide oncogene pathway peptide phenotype pheromone pheromone response phospholipase phosphorylation plasmid prep probe Proc promoter protein kinase purified ras proteins receptor region regulation regulatory residues role Saccharomyces cerevisiae Sec4 serum shown signal transduction specific STE2 gene STE3 STE4 stimulation strain structure Struhl subunit synthesis tein tion trans transcription factor transcriptional activation transfected transformed vitro wild-type yeast YPT1 тм