Collected reprints, 1902-1925

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Page 314 - The problem of the general nature of anesthesia is a fact inseparable from the wider problem of the nature and conditions of irritability in general.
Page 217 - ... increased by any means undergoes depolarization, and it is to be assumed that this region, acting then as cathode, influences electrically the adjoining regions, depolarizing these in turn and causing a corresponding increase in permeability; in this manner the effect is propagated along the membrane M at a rate which in any particular case will evidently depend on the sensitivity or quickness of response of the tissue — ie, in general on the duration of the latent period of stimulation: when...
Page 165 - A SIMPLE CASE OF SALT ANTAGONISM IN STARFISH EGGS. BY RALPH S. LILLIE. (From the Marine Biological Laboratory, Woods Hole, and the Nela Research Laboratories, Nela Park, Cleveland.) (Received for publication, April 23, 1921.) The freshly laid egg of the common starfish...
Page 387 - ... the anterior region of these organs . . . together with a portion of the adjoining septum, constitutes the primitive nephrostome, from which the adult nephrostome is directly derived." The terminal vesicle is also not ectoblastic, but " is formed as a differentiation of the most posterior • portion of the primitive nephridium. There is no ectodermal invagination...
Page 318 - Lillie advocates an extension of the theory of Faraday and de la Rive, that the transmission of the excitation state from the immediate site of activity to the adjoining resting area is dependent on an electrical local action of the same essential nature as that which is responsible for the etching or corrosion of non-homogeneous metallic surfaces, such as iron in contact with an electrolyte solution; and if this be true, the rate of nerve conduction should be a function of the electrical conductivity...
Page 357 - ... advantageous when working under a high fall. The kinetic energy is the only form in which the gravity can be applied advantageously to the performance of mechanical work under a small fall. The motors using it in this form are the common undershot wheel, the Poncelet water-wheel, and the turbines. It will be sufficient for the purpose of this paper to give the efficiency of the various types of water motors for any fall, without going into a detailed description of those which are unsuitable...
Page 364 - ... of the plasma membranes of the cells or irritable elements, of such a kind as to render these membranes more resistant toward agencies that under the usual conditions rapidly increase their permeability; cytolysis and stimulation, both of which depend on such increase of permeability, are hence checked or prevented. Decrease in the readiness with which the permeability is increased thus involves for an irritable tissue decreased irritability; this effect is produced by various salts, eg, of magnesium,...
Page 205 - R* and R, in the diagram). The observed electrical conductivity of any solution is directly proportional to the distance between the electrodes. Cf. Carlson, " Evidence of the Fluidity of the Conducting Substance in Nerve,
Page 202 - See below, p. 221. irritable living tissue is to be regarded as an electrolytic conductor subdivided by semi-permeable membranes. A current traversing such a system can produce decided changes only at the semi-permeable partitions, ie, the plasma membranes of the cells or elements, where the movement of ions is blocked or checked. The current carries ions to the membrane, producing increased concentration of cations on the side directed toward the anode and of anions on the opposite side; this tendency...
Page 106 - CERTAIN MEANS BY WHICH STARFISH EGGS NATURALLY RESISTANT TO FERTILIZATION MAY BE RENDERED NORMAL AND THE PHYSIOLOGICAL CONDITIONS OF THIS ACTION. RALPH S. LILLIE. (From the Marine Biological Laboratory, Woods Hole, and the Physiological Laboratory, Department of Zoology, University of Pennsylvania.) Last summer at Woods Hole, while investigating the influence of ether and other anaesthetics in protecting the unfertilized eggs of starfish against the cytolytic action of pure isotonic sodium chloride...

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