Comparative Genomics and Proteomics in Drug Discovery, Issue 58Comparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds. |
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Contents
The practical implications of comparative kinetoplastid genomics | 25 |
The relevance of host genes in malaria | 47 |
Nicotinic acetylcholine receptors as drugchemical targets | 93 |
Copyright | |
22 other sections not shown
Other editions - View all
Comparative Genomics and Proteomics in Drug Discovery, Volume 58 John Parrington,Kevin Coward Limited preview - 2018 |
Common terms and phrases
Acad Sci USA adhesion African allele analysis annotation antibodies antigens associated Biol biology biomarkers blood brain Caenorhabditis elegans cerebral malaria chabaudi Chagas disease chromosome clinical comparative genomics cytokines drug development drug discovery drug targets drug-target discovery DrugBank El-Sayed encoded endogenous diseases enzyme erythrocytes eukaryotic expression function GelScape gene families genetic genome projects genome sequences host human identified IFN-y Immunol Infect Immun inhibit interactions iRBCs kinetoplastid Kwiatkowski Leishmania levels macrophages major malaria infection mammalian metabolic microarray molecular molecules mutations nAChR subunits Natl Acad Sci Nav channels neonicotinoids neuronal nicotinic acetylcholine receptor nicotinic receptor nitric oxide Nucleic Acids Res omic parasite pathogens pathways PECAM-1 Plasmodium chabaudi Plasmodium falciparum polymorphisms potential Proc Natl Acad protection protein Proteomics RBCs role Sattelle severe malaria silico sleeping sickness sodium channel species structure studies synteny therapeutic Tritryp Trypanosoma brucei Trypanosoma cruzi trypanosomatids tumor necrosis factor vaccine vivo
Bibliographic information
| Title | Comparative Genomics and Proteomics in Drug Discovery, Issue 58 Comparative genomics and proteomics in drug discovery Issue 58 of Experimental biology reviews Volume 58 of SEB symposium series Issue 58 of Symposia of the Society for Experimental Biology |
| Editors | John Parrington, Kevin Coward |
| Edition | illustrated |
| Publisher | Taylor & Francis Group, 2007 |
| Original from | the University of Virginia |
| Digitized | Jun 18, 2008 |
| ISBN | 0415396530, 9780415396530 |
| Length | 182 pages |
| Subjects | › › Medical / Pharmacology Science / Life Sciences / Genetics & Genomics |
| Export Citation | BiBTeX EndNote RefMan |