Comparative Genomics and Proteomics in Drug DiscoveryComparative Genomics and Proteomics in Drug Discovery gives an overview of how emerging genomic and proteomic technologies are making significant contributions to global drug discovery programs, and in particular the key role that comparative genomics and proteomics play within this strategy. Each chapter is written by respected authorities, with hands-on experience, from both academic and pharmaceutical backgrounds. |
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Contents
The practical implications of comparative kinetoplastid genomics | 25 |
The relevance of host genes in malaria | 47 |
contributions from comparative genomics forward and reverse genetics | 93 |
Copyright | |
22 other sections not shown
Other editions - View all
Comparative Genomics and Proteomics in Drug Discovery, Volume 58 John Parrington,Kevin Coward Limited preview - 2018 |
Comparative Genomics and Proteomics in Drug Discovery, Volume 58 John Parrington No preview available - 2019 |
Common terms and phrases
acetylcholine receptor Acids activity addition African allele analysis annotation antigens approach associated BASys binding biology blood brain brucei cause cells channels chromosome clinical comparative complete contains cruzi databases determine discovery disease domains drug targets effective erythrocytes et al example expression factor Figure function gene genetic genome glycophorin host human identified immune Immunol important increased infection interactions involved known Leishmania levels major malaria molecular molecules mutations nACHR Nature neuronal nicotinic acetylcholine organisms parasite Parasitol pathways patients Plasmodium falciparum polymorphisms populations possible potential present production protection protein Proteomics RBCs recent receptor regions resistance response RNAi role selective sequence severe shown silico similar species stage structure studies subtypes subunits suggest surface tests tion treatment Trypanosoma trypanosomatids vaccine variants View
Bibliographic information
| Title | Comparative Genomics and Proteomics in Drug Discovery Issue 58 of Experimental biology reviews Volume 58 of SEB symposium series Issue 58 of Symposia of the Society for Experimental Biology |
| Editors | John Parrington, Kevin Coward |
| Edition | illustrated |
| Publisher | Taylor & Francis Group, 2007 |
| Original from | the University of Virginia |
| Digitized | Jun 18, 2008 |
| ISBN | 0415396530, 9780415396530 |
| Length | 182 pages |
| Subjects | › › Science / Life Sciences / Genetics & Genomics |
| Export Citation | BiBTeX EndNote RefMan |