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Directly Acting Alkylating Agents
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administration adult alkylating animals aromatic aryl hydrocarbon hydroxylase benzo(a)pyrene binding Biochem biotransformation birth brain Cancer Cancer Inst Cancer Res carbon monoxide carcinogenesis carcinogenic cells chemical cigarette smoke compounds concentration cytochrome diethylnitrosamine diethylstilbestrol DMBA Druckrey embryo enzymes ependymomas estrogens ethylnitrosourea experimental exposure fetal tissues fetus fetuses gliomas golden hamsters Gynecol human placenta immunized incidence increased induced tumors injection investigations Ivankovic Juchau kidney Krebsforsch leukemia liver lung malignant maternal smoking membrane metabolic activation metabolites methyl mg/kg microsomal mixed gliomas monooxygenation mothers mouse NCI Natl neonatal neoplasms nephroblastomas nervous system neurinomas newborn nicotine nitrosamines nonsmokers Obstet offspring oncogenic organs oxidative Pharmacol placental placental tissues pregnancy pregnant hamsters pregnant rats prenatal progeny rabbits radioactivity reactions respiratory smoking during pregnancy species steroidal studies substrates Syrian golden hamsters Syrian hamsters teratogenic trachea tract transplacental transplacental carcinogenesis transplacental carcinogenic effect Transplacental effects transplacentally induced treatment virus vitro xenobiotic