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G Fey H Domdey K Wiebauer A S Whitehead and K Odink
H R Colten
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Acad Sci USA aggregation alternative complement pathway alternative pathway amino acid anaphylatoxins antibody antigen assay binding biologic biosynthesis blood bound C3 convertase C3 gene C3b receptor C3bi cDNA cellular chain Cl-In classical pathway cleavage cleaved Clin Invest Colten HR complement activation complement components complement proteins complement receptors complement system component of complement component of human culture deficiency detected effect enhance enzyme erythrocytes Factor H Fearon DT fragments function genetic guinea pig human C3 human complement human serum immune complexes immunoglobulin Immunol Immunology inactivation incubated induced infected inhibition interaction leukocytes lipid lymphocytes lysis macrophages mechanism mediated molecular weight molecules monocytes mouse Muller-Eberhard HJ murine Natl Acad Sci neutrophils normal patients peptide peritoneal macrophages plasma plasmin platelets poly C9 Proc Natl Acad properdin proteases purified rabbit radiolabeled reaction release residues role sequence specific structure studies subunit synthesis thiolester tissue virus viruses vitro zymosan