Computation of biomolecular structures: achievements, problems, and perspectives
Dikeos Mario Soumpasis, Thomas M. Jovin
Springer-Verlag, 1993 - Computers - 252 pages
The material in the book covers a deliberately wide range of topics concerning the study and modelling of biomolecules (DNA, RNA, Proteins) using computer techniques. Methods for structure determination and predictions, the analysis of structure-sequence databases and the computer based design of molecules are presented along with approaches for modeling the dynamic behavior of biomolecules and treating complex solvent effects on their structure in solution. Several specific system applications illustrate what can be presently achieved. The reader can obtain a good feeling of what is happening in a very active research area at the intersection of molecular biology, physical chemistry and computer science, and obtain valuable information not otherwise easily accessible due to its very diversified interdisciplinary character.
What people are saying - Write a review
We haven't found any reviews in the usual places.
Structure Analysis and Prediction
Physical Chemistry and Dynamics
1 other sections not shown
Other editions - View all
Acad Sci USA algorithm alignment length analysis anharmonic atoms average B-DNA backbone structure base pair base sequence binding Biomol biomolecular Biopolymers Bode calculated Cartesian chain Chem complexes conformation coordinate frame correlation crambin crystal structure cumulative density curve database defined Diekmann distance distribution DNA Four-Way Junctions DNA oligomers double helical electrostatic EMBO entropy equation experimental exponent Figure free energy geometry global helical axis helix homology homology threshold Huber hydrogen bonds inhibitor interactions interface areas ionic Kitzing ligand lysozyme macromolecule matrix method minor groove Mol Biol molecular dynamics molecule Monte Carlo Natl Acad Sci nucleic acid Nucleic Acid Structure oligomers optimisation ovomucoid parameters partition function PMF's potential energy power law Proc Natl Acad protein structures residues rotations secondary structure sequence similarity simulation solvent Soumpasis specific stacked stem tertiary structure thermodynamic torsional angles trajectory values vector vibrational vinylexin vKitzing