Connectome: How the Brain's Wiring Makes Us who We are

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Houghton Mifflin Harcourt, 2012 - Psychology - 359 pages
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The bold and thrilling quest to finally understand the brain
We know that each of us is unique, but science has struggled to pinpoint where, precisely, our uniqueness resides. Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?
Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain s neurons, which change slowly over time as we learn and grow. The connectome, as it s called, is where our genetic inheritance intersects with our life experience. It s where nature meets nurture.
Seung introduces us to the dedicated researchers who are mapping the brain s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking the scientific equivalent of climbing Mount Everest but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are wired differently, but nobody knows for sure. The brain s wiring has never been seen clearly.
In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to upload their minds into computers, achieving a kind of immortality.
"Connectome "is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience. "

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User Review  - fpagan - LibraryThing

Pop neuroscience: the future possibility and value of mapping a human brain's network of 10^11 neurons and 10^15 synapses. Most notably, the last two chapters discuss cryonic preservation and mind ... Read full review

CONNECTOME: How the Brain's Wiring Makes Us Who We Are

User Review  - Jane Doe - Kirkus

The key to understanding how brains work, writes Seung (Computational Neuroscience/MIT), is in the wiring.The author champions the study of "connectomes," the unique wiring diagrams of individual ... Read full review


Nature and Nurture
Beyond Humanity
End Matter
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About the author (2012)

Sebastian Seung is Professor of Computational Neuroscience at MIT and an Investigator of the Howard Hughes Medical Institute. He has made important advances in robotics, neuroscience, neuroeconomics, and statistical physics. His research has been published in leading scientific journals, and also featured in the New York Times, Technology Review, and the Economist .

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