Contemporary Challenges in Autoimmunity, Volume 1173

Front Cover
Yehuda Shoenfeld, M. Eric Gershwin
John Wiley & Sons, Oct 5, 2009 - Medical - 400 pages
This volume features key presentations from the 6th International Congress of Autoimmunity. The International Congress of Autoimmunity has become established as one of the major meetings in the field of immunology, with presentations covering every aspect of basic research in the hopes of clarifying pathogenesis of autoimmune disease as well as providing information on the latest innovations in biological and other modes of treatment. The goal of this volume is to present cutting edge research that focuses in particular on newer diagnostic tools and newer therapies for human autoimmune disease.

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Contents

Contemporary Challenges in Autoimmunity
1
The Past the Present and
10
Accuracy of the First Fully Automated Method for Anticardiolipin and Antiβ2
21
Assay
28
Celiac G+ Antibody Assay for the Detection of Autoantibodies in Celiac Disease
36
Highsensitivity Detection of Autoantibodies Against Proteinase3 by a Novel
41
AntiC1q Autoantibodies in Lupus Nephritis By Renato Alberto Sinico Laura
50
Correlation Between Clinical Activity and Serological Markers in a Wide Cohort
60
Oversecretion of Cytokines and Chemokines in Lupus Nephritis Is Regulated
449
Tolllike Receptors in Multiple Sclerosis Mouse Experimental Models By Monica
458
A New Dimension in the Pathogenesis of Psoriasis
470
Effector Functions of Antiaquaporin4 Autoantibodies in Neuromyelitis Optica
478
Are Regulatory T Cells the Answer?
487
Shared and Unique Gene Expression in Systemic Lupus Erythematosus
493
Association of Polymorphisms in Interleukin10 Gene Promoter with
501
ValLeu247 Polymorphism of β2glycoprotein I in Brazilian Patients with
509

Circulating Cardiac TroponinI Autoantibodies in Human Plasma and Serum
67
Choroid Plexus Connexin 43 Expression and Gap Junction Flexibility
75
Autoantigens Identified by Screening a Human Heart cDNA Library with Acute
83
Optimization of Highthroughput Autoantibody Profiling for the Discovery
92
White Blood Cell Count Abnormalities and Infections in Oneyear Followup
103
An Italian Multicenter Study for Application of a Diagnostic Algorithm
124
Clinical and Immunogenetic Associations in Down
130
Possible Involvement of Chemokineinduced Platelet Activation in Thrombophilic
137
Prevalence of Anticardiolipin Antibodies in Patient Cohorts with Distinct Clinical
146
Characterization of Antibodies Directed against the Immunoglobulin Light
152
DNABound Lactoferrin Is the Major Target for Antineutrophil Perinuclear
161
Autoantibody Screen in Inflammatory Myopathies High Prevalence of Antibodies
174
High Sensitive Detection of DoubleStranded DNA Autoantibodies by a Modified
180
The Incidence of Celiac Disease Antibodies in Plasma Specimens with
186
A Report of Three
199
Cognitive Functioning in Behcets Disease By Sara Cavaco Ana Martins da Silva
217
Alexithymia in Systemic Lupus Erythematosus Patients By Filipe Barbosa
227
AntiC1q Antibodies in JuvenileOnset Systemic Lupus Erythematosus By A
235
Relevance of AntiC1q Autoantibodies to Lupus Nephritis By Alexandra
243
Dysregulation of the Vitamin D Nuclear Receptor May Contribute to the Higher
252
Reversing Bacteriainduced Vitamin D Receptor Dysfunction Is Key
259
How Do They Work? By Sebastien
260
BLymphocyte Stimulator and a ProliferationInducing Ligand Serum Levels
268
Cytokines and Anxiety in Systemic Lupus Erythematosus SLE Patients
286
Natural Antibodies against Phosphorylcholine in Cardiovascular Disease By
292
CXCR3 Inflammation and Autoimmune Diseases By Stephanie Lacotte Susana
310
Clonal CD27+ CD19+ B Cell Expansion through Inhibition of FCγIIR
326
Alterations in Cytokine Profile and Dendritic Cells Subsets in Peripheral Blood
334
Experimental Myth or Clinical Truth?
343
Chemokines as Novel Therapeutic Targets for Inflammatory Bowel Disease
350
Galectin10 Eosinophils and Celiac Disease By Valli De Re Maria Paola
357
Defensins in Systemic Lupus Erythematosus By Oren Froy
367
Sex Differences in a Murine Model of Sjogrens Syndrome By Daniela ˇCihakova
378
Metabolites as Clinical Markers in Autoimmune and Chronic Disease
384
Induction of Arthritogenic
391
Humoral Mechanisms of Atherogenesis By Joana R Batuca Marta C Amaral
401
Microparticles and the Hygiene Hypothesis By Pablo I Martın Pablo Alejandro
409
Hyperactivity Induced by Antiphospholipid Syndrome Serum By Assaf
422
The Role of iNKT Cells in the Immunopathology of Systemic Lupus
435
A Role for Natural Autoantibody
442
Association Study on Two Vitamin D Receptor Gene Polymorphisms and Vitamin
515
Genetic Susceptibility Loci in Rheumatoid Arthritis Establish Transcriptional
521
Genetic and Epigenetic Control of the Major Histocompatibility Complex Class
538
Human Leukocyte AntigenDRB1 and DQB1 Genotyping in Lupus Patients
545
Race Differences in Immunogenetic Features and Photosensitivity of Cutaneous
552
HLAB27 and HLAB51 Determination in Tunisian Healthy Subjects
564
An Animal Model Mimicking Gut and Joint
570
Ankylosing Spondylitis Susceptibility and SeverityContribution of TNF Gene
581
Autoantibodies Polymorphisms in the Serotonin Pathway and Human Leukocyte
589
Infection Vaccination and Autoantibodies in Chronic Fatigue Syndrome Cause
600
Immunizations in Adult Patients with Systemic Sclerosis By Odile Launay Loic
610
Influenza and Autoimmunity By Nataˇsa Toplak and Tadej Avˇcin
619
The Role of Infections in the Immunopathogensis of Systemic SclerosisEvidence
627
Infectious Serologies and Autoantibodies in Wegeners Granulomatosis and Other
649
Exposure to EpsteinBarr Virus Infection Is Associated with Mild Systemic Lupus
658
Sugarfree AntibodiesThe Bacterial Solution to Autoimmunity? By Maria
664
Infections May Have a Protective Role in the Etiopathogenesis of Celiac Disease
670
Rituximab in Severe Pemphigus By Enno Schmidt Matthias Goebeler
683
Clinical Biologic
692
Rituximab Therapy in Primary Sjogrens Syndrome By Cristina Alcˆantara
701
Four Case Reports
712
Improvement of Rituximab Efficiency in Chronic Lymphocytic Leukemia
721
A New Concept in Therapeutics
729
Statins for the Treatment of Antiphospholipid Syndrome? By Praveen Jajoria
736
Influence of Statins on MHC Class I Expression By Pratibha Singh Danielle
746
Proliferation Signal Inhibitors for the Treatment of Refractory Autoimmune
752
Colchicine Revisited By Anupama Bhat Stanley M Naguwa Gurtej S Cheema
766
A New Bone Marrow Transplantation Method for Stem Cell Disorders
774
A Novel Synthetic Steroid as an Oral Treatment for Autoimmune
781
A Fusion Protein Composed of IL2 and Caspase3 Ameliorates the Outcome
791
Treatment of Rat Adjuvant Arthritis with Flavonoid Detralex Methotrexate
798
In Vitro Effects of Antiphospholipid SyndromeIgG Fractions and Human
805
Effects of Biologics on Vascular Function and Atherosclerosis Associated with
814
Predictors of Damage Progression in Portuguese Patients with Systemic Lupus
822
An Openlabel Study Adding Creatine Monohydrate to Ongoing Medical
829
TNFα Antagonist Survival Rate in a Cohort of Rheumatoid Arthritis Patients
837
Treatment with PEGinterferon and Ribavirin for Chronic Hepatitis C Increases
847
CpG ODN Enhances the Efficacy of Rituximab in NonHodgkin Lymphoma
858
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About the author (2009)

Yehuda Shoenfeld is the Incumbent of the Laura Schwarz-Kipp Chair of Research of Autoimmune Diseases, Sackler Faculty of Medicine, Tel Aviv University in Tel Aviv, Israel. He is also Founder of the Center for Autoimmune Diseases, both at the Sheba Medical Center in Tel Hashomer, Israel.

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