Coronary Heart Disease Epidemiology: From Aetiology to Public Health

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M. G. Marmot, Paul Elliott
Oxford University Press, 2005 - Medical - 932 pages
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Coronary heart disease is the leading cause of death worldwide affecting millions of people in both developed and developing countries. The dual aims of this book are to review the well-established and emerging risk factors in coronary heart disease and to apply this knowledge to publichealth approaches to disease prevention. The book includes authoritative accounts of studies within a single population and international studies, important areas of methodological development, trials to test preventive strategies, and the application of epidemiological and other knowledge to thedevelopment of public health policy for the prevention of widespread disease. It is an all-encompassing work containing contributions from the world authorities in the field. The book is divided into four sections. The introduction reviews advances in the understanding of, and the current status, of risk factors for CHD. Section 2 looks at recent global trends and emerging patterns of CHD morbidity and mortality in several countries, and includes chapters on work doneunder the auspices of WHO on the global burden of disease in relation to smoking and blood pressure. Section 3 focuses on advances in understanding the aetiology of CHD with each chapter focused on a particular risk factor. Section 4 explores measures of prevention and intervention in terms ofpublic health policy with specific examples from around the world.
 

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Contents

Contribution of epidemiology to understanding coronary heart disease
8
six established major risk factors and low risk
32
Global picture of coronary heart disease
71
Trends in Asia
102
Coronary heart disease burden among persons of African origin
118
global
135
Blood pressure and the burden of coronary heart disease
152
Lipids and cholesterol
174
Seasonal variations in allcause and cardiovascular mortality and the role
495
apolipoprotein E
528
The developmental origins of coronary heart disease
547
Life course influences on coronary heart disease
568
Emergence of risk factors in children
591
Risk factors in the elderly
606
the individual and the population
631
major risk factors and the potential
642

a comparison between
187
Dietary patterns and coronary heart disease risk
207
Antioxidants and cardiovascular disease
220
Serum homocysteine and coronary heart disease
239
Alcohol and coronary heart disease
251
Fish consumption n3 fatty acids and coronary heart disease
264
history of a hypothesis
275
Haskell
286
Metabolic syndrome diabetes and coronary heart disease
311
Women and cardiovascular heart disease
331
Use of oral contraceptives
348
Systematic review of prospective cohort studies of psychosocial factors
363
Mental illness and coronary heart disease
414
Psychophysiology
432
Chronic infection and circulating markers of inflammation
448
Coagulation thrombosis and coronary heart disease
466
Air pollution
480
findings from the Nurses Health Study
654
Risk scores for management and prevention of cardiovascular disease
669
Noninvasive measures of preclinical coronary heart disease
688
Screening for future coronary heart disease
706
Screening for type 2 diabetes
714
Primary prevention of high blood pressure
757
The secondary prevention of cardiovascular disease
769
Smokefree policies are an effective way to reduce heart disease rapidly
792
national strategies for dietary change
805
Lessening inequalities and effect on coronary heart disease 879
819
Behaviour change
831
treatment
850
hypertension
865
Community change and the role of public health
893
Index
909
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About the author (2005)

Michael Marmot is at Department of Epidemiology and Public Health, University College, London, UK. Paul Elliott is at Professor of Epidemiology and Public Health, Imperial College of Science, Technology and Medicine, London, UK.

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