Cytokines and Bone Metabolism

Front Cover
CRC Press, Dec 18, 1991 - Medical - 432 pages
Cytokines and Bone Metabolism presents a comprehensive review of the research done to date on the role of cytokines in bone metabolism. All of the major groups of cytokines and growth factors are covered, and more than 2,000 references are included. In each chapter, the biochemistry and wider cellular actions of individual factors are reviewed before data detailing the in vitro and in vivo actions in bone are presented. Extensive reviews of the cell biology of bone, the potential role of cytokines in bone diseases, and the theoretical and practical possibilities for pharmacological intervention based on cytokines as targets are also provided. Cytokines and Bone Metabolism is an indispensable reference for researchers and students in a wide range of medical fields.
 

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Contents

Chapter
2
A Bone Resorption
3
Systemic and Local Factors Which Regulate Bone Cell
14
The Regulation of Bone Remodeling
26
and Tumor Necrosis Factor
71
Chapter 3
93
Chapter 4
109
Epidermal Growth Factor and Transforming Growth Factoro
147
Chapter 8
185
Chapter 9
229
Chapter 10
267
Chapter 11
299
Chapter 12
325
Chapter 13
361
Chapter 14
383
Index
407

Chapter 7
171

Common terms and phrases

Bibliographic information