Cytopathology of Bone and Soft Tissue Tumors

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Oxford University Press, 2002 - Medical - 266 pages
Cytopathology of Bone and Soft Tissue Tumors provides the practicing pathologist with a single reference for describing and illustrating the cytologic features of musculoskeletal tumors. Using fine-needle aspiration (FNA), the approach of this work is encyclopedic: both relatively common and relatively rare lesions are depicted. It is expected that Cytopathology of Bone and Soft Tissue Tumors will serve to widen the usage of the FNA technique which can: substantially decrease patient morbidity; lessen the complications that arise due to other biopsy techniques; and shorten the time as well as expense required for diagnosis.
The chapters on soft tissue lesions are organized by direction of differentiation. Each chapter documents both the common and uncommon lesions within the tissue group. Summaries of clinical findings are given along with the histopathologic and cytologic description. Key diagnostic points (in tabular form) and a discussion of the differential diagnosis complete each section.
The section on skeletal lesions is organized along predominant cell type seen in smears. This approach facilitates grouping of lesions into diagnostically useful categories, allowing the pathologist faced with an unfamiliar lesion to rapidly access the portion of the text most useful for differential diagnosis. Within each chapter, the organization is similar to that within the soft tissue chapters. The introduction discusses technical concerns, limitations of the technique, and a diagnostic approach in both tabular and narrative form. Information on grading of soft tissue sarcomas completes the introduction.
 

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Contents

Introduction
3
Bone Lesions
4
Soft Tissue Lesions
5
Grading
7
Technical Considerations
8
Approach to the Cytologic Diagnosis of Musculoskeletal Lesions
12
Cytologic Appearance of Normal Mesenchymal Tissues
22
Striated Muscle
23
Angiosarcoma
141
Soft Tissue Neoplasms of Miscellaneous Types
146
Ganglion Cyst
148
Synovial Sarcoma
149
Melanoma of Soft Tissues Clear Cell Sarcoma of Tendon Sheath
152
Alveolar Soft Part Sarcoma
155
Epithelioid Myxoid
157
Extrarenal Rhabdoid Tumor
160

Smooth Muscle
24
Peripheral Nerve
26
Fibrous Tissue
28
Cartilage
29
Bone
30
Reactive Proliferations and Neoplasms of Fibrous Tissue
34
Proliferative Fasciltis and Proliferative Myositis
37
Myositis Ossificants
39
Elastofibroma Dorsi
41
Myofibroma and Myofibromatosis
42
Fibromatoses Abdominal and ExtraAbdominal Desmoid Tumor
43
Solitary Fibrous Tumor
46
Fibrous Hamartoma of Infancy
47
Fibrosarcoma
49
Myxofibrosarcoma
51
Fibrohistiocytic Neoplasms
53
Tenosynovial Giant Cell Tumor Diffuse and Localized Giant Cell Tumor of Tendon Sheath and Pigmented Villonodular Synovitis
55
Dermatofibrosarcoma Protuberans
58
Angiomatoid Fibrous Histiocytoma
60
Malignant Fibrous Histiocytoma
62
Giant Cell Fibroblastoma
68
Lipomatous Neoplasms
71
Variants of Lipoma
73
Lipoma of Tendon SheathJoints Lipoma Arborescens
74
Spindle Cell Lipoma
75
Pleomorphic Lipoma
76
Myelolipoma
77
Hibernoma
78
Lipoblastoma
79
Liposarcoma
80
Neoplasms of Smooth Muscle
89
Vascular Leiomyoma Angiomyoma
90
Epithelioid Smooth Muscle Tumors Leiomyoblastoma
92
Palisaded Myofibroblastoma
94
Leiomyosarcoma
95
Tumors of the Peripheral Nerves and Primitive Neuroectodermal Tumors
100
Neurofibroma
105
Perineurioma
107
Granular Cell Tumor
108
Malignant Peripheral Nerve Sheath Tumor Malignant Schwannoma Neurofibrosarcoma
110
Malignant Peripheral Primitive Neuroectodermal Tumor
113
Ectomesenchymoma
116
Neoplasms of Striated Muscle
119
Rhabdomyosarcoma
121
Alveolar Rhabdomyosarcoma
126
Pleomorphic Rhabdomyosarcoma
128
Vascular Neoplasms of Soft Tissue
131
Glomus Tumor
134
Kaposis Sarcoma
136
Hemangiopericytoma
138
Extraskeletal Myxoid Chondrosarcoma
162
Soft Tissue Chondroma
164
Carilaginous Tumors
168
Infantile Cartilaginous Harmartoma of the Rib
170
Chondromyxoid Fibroma
171
Osteochondroma
173
Synovial Chondromatosis
175
Chondroblastoma
176
Chondrosarcoma
178
Chondrosarcoma Variants
183
Chordoma
187
Myxoid Chondrosarcoma
190
OsteoidProducing Lesions
193
Osteoid Osteoma
195
Osteosarcoma
197
Conventional Intramedullar Osteosarcoma Not Otherwise Specified
204
Telangiectatic Osteosarcoma
205
Periosteal Osteosarcoma
206
Other Lesions
208
Ossifying Fibromyxoid Tumor
210
Giant CellContaining Lesions
212
Solid Aneurysmal Bone Cyst
214
Giant Cell Reparative Granuloma
215
Conventional Giant Cell Tumor of Bone
216
Chondroblastoma
219
Nonossifying Fibroma and Fibrous Cortical Defect
221
Pigmented Villonodular Synovitis
223
Small Cell Neoplasms of Bone
225
NonHodgkins Lymphoma
228
Myeloma
231
Eosinophilic Granuloma Langerhans Histiocytosis
233
Small Cell Osteosarcoma
234
Melanotic Neuroectodermal Tumor of Infancy
235
Cystic Lesions of Bone
238
Aneurysmal Bone Cyst
239
Intraosseous Ganglion Cyst
240
Subchondral Osteoarthritic Bone Cysts
241
Bone Lesions Composed Predominantly of SpindleShaped Cells
243
Intraosseous Demoplastic Fibroma
245
Other Uncommon Predominantly Spindle Cell Lesions Affecting Bone
246
Vascular Neoplasms of Bone
248
Other Benign Vascular Lesions
250
Angiosarcoma
252
Metastatic Disease
255
Carcinoma of the Prostate
256
Carcinoma of the Lung
257
Carcinoma of the Thyroid
258
Synovial Metastases
259
Index
261
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Page 254 - Rosai J, Gold J, Landy R. The histiocytoid hemangiomas: a unifying concept embracing several previously described entities of skin, soft tissue, large vessels, bone, and heart. Hum Pathol 10:707, 1979.

About the author (2002)

Lester J. Layfield is at University of Utah Medical School. Tina Fanning is at The MD Anderson Cancer Center, Houston.

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