DNA Tumor Viruses

Front Cover
Blossom Damania, James Pipas
Springer Science & Business Media, Dec 19, 2008 - Medical - 798 pages

DNA Tumor Viruses will focus on the DNA viruses in the human population that are associated with cancers. It will cover most of the viruses that are thought to contribute to human malignancy.

This book will represent a comprehensive review of the field of DNA tumor virology. Right now, while there are books out there that cover individual viruses that will be also covered in this book, there is no single book that covers this topic comprehensively.

The main textbook in this market, Fields, which is referred to by both reviewers, covers some of these topics but on a lower level. The only two books that are nearly as comprehensive as this one are Human Tumor Viruses, which was published by the American Society for Microbiology in 1998 and is quite outdated, and Viruses, Cell Transformation, and Cancer, which was published by Elsevier in 2001. Our book will be the only current, comprehensive review of its kind in the market.

 

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Contents

Polyomavirus Life Cycle
1
Transformation by Polyomaviruses
25
Polyomaviruses and Disease
53
The Life Cycle of Human Papillomaviruses
75
Papillomavirus Transformation
105
Biology Diversity and Pathogenesis
127
Adenovirus Transformation
145
Overview of the Large DNA Tumor Viruses
163
EBV Immunotherapy
379
KSHV Epidemiology and Subtype Evolution
403
Introduction to Diseases Associated with Kaposis SarcomaAssociated Herpesvirus
441
Organization and Expression of the Kaposis SarcomaAssociated Herpesvirus Genome
469
KSHV Latent Genes and Their Regulation
495
Regulation of Expression Mode of Action and Downstream Targets of ORF50 Protein in KSHV Lytic Cycle Activation
521
HHV8KSHV Proteins Involved in Signaling and Transformation
555
KSHV Entry and Infection of Target Cells
583

Epidemiology of EBV Infection
205
EBV Diseases
217
The EpsteinBarr Virus Genome
241
Biologic Properties and Contribution to Oncogenesis
259
The EpsteinBarr Virus Lytic Life Cycle
285
Genome Maintenance and Regulation of Lymphocyte Cell Growth and Survival
317
EpsteinBarr Virus Entry
355
KSHV Immune Evasion
611
Noncoding Regulatory RNAs of the DNA Tumor Viruses
645
AIDS and Associated Malignancies
683
Primate Models for GammaherpesvirusAssociated Malignancies
703
A Small Animal Model for Characterizing Basic Aspects of Gammaherpesvirus Pathogenesis
735
Index
777
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