Dance to the Tune of Life: Biological Relativity

Front Cover
Cambridge University Press, 2017 - Medical - 283 pages
Cover -- Half title -- Title -- Copyright -- Contents -- Preface -- Acknowledgements -- 1 The Universe and the Principle of Relativity -- The Sky at Night -- Early Cosmologies -- The Copernican Revolution -- Galileo: Father of Modern Science -- The Earth from a Billion Miles -- Newton's Laws of Motion -- Nineteenth-Century Certainties -- Quantum Mechanics -- Einstein's Special Theory of Relativity -- Einstein's General Theory of Relativity -- Can We 'Feel' the Consequences of Relativity? -- Hubble's Deep Field Views -- Conclusions -- 2 Biological Scales and Levels -- The Sense of Scale -- Scales and Levels -- Atoms and Ions -- Molecules -- Molecules as Systems -- Networks -- Organelles -- Cells -- Tissues -- Organs -- Whole-Body Systems -- The Organism as a Whole -- Beyond Organisms -- Conclusions -- 3 Biological Networks -- Networks are not Diagrams! -- How Do Complex Structures Form? -- Biological Oscillators and Attractors -- Circadian Rhythm -- Cardiac Rhythm -- Gene Expression Patterns -- Synchronisation of Oscillators: Brainwaves -- Chance at the Heart of the Cell -- Conclusions -- 4 Nature and Origin of Cells -- The Medical Histology Class -- Cells as Carriages -- The Simplest Cells: Bacteria and Archaea -- Bacteria -- Archaea -- Eukaryotes: The Largest Organisms but the Smallest Domain -- The Cell Cycle -- Meiosis -- RNA and Other Early Worlds? -- How Cells Form Tissues -- The Nearly Cells: Viruses -- Tree, Networks or Rings of Life? -- The Death of Cells -- Conclusions -- 5 Blind Chance and Natural Selection -- Charles Darwin and his Predecessors -- Darwin on Lamarckism -- The Rise of Neo-Darwinism Leading to the Modern Synthesis -- Evolution and Genetics -- The Modern Synthesis -- Schrödinger and What is Life? -- Neo-Darwinism and the Central Dogma -- The Language of Neo-Darwinism -- The Language of Neo-Darwinism as a Whole
 

Contents

Biological Scales and Levels
30
Biological Networks
69
Biological Oscillators and Attractors
77
Nature and Origin of Cells
97
RNA and Other Early Worlds?
113
5
121
Evolution and Genetics
129
NeoDarwinism and the Central Dogma
136
Biological Relativity
160
Natural Genetic Engineering
187
Epigenetics and a Relativistic Theory of Evolution
214
The Meaning of It All
247
Postscript
268
Index
276
Copyright

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About the author (2017)

Denis Noble, CBE, FRS, is Emeritus Professor of Cardiovascular Physiology and Director of Computational Physiology at the University of Oxford. He is one of the founders of the field of systems biology and is the current President of the International Union of Physiological Sciences (IUPS).