Defending Life: The Nature of Host-Parasite Relations

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Springer Science & Business Media, May 11, 2007 - Medical - 241 pages
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Defending Life discusses the relationship between hosts and parasites. A major contention of the book is that the immune system depends ontologically on the ecosystem in which it is embedded; it would not have the features it has if it was not related in one way or other to parasitic agents and to the host’s own cells and tissues. To sustain the argument, life is investigated at all layers – from molecules up through cells, organisms and ecosystems. Together with the inverse course, which goes from ecological contingencies down to gene-expression profiles, the approach facilitates an advanced understanding of immunocompetence as well as its converse, immunoincompetence. The emphasis on analytical abstractions, coherent patterns and generative mechanisms makes possible the distinction between genuine causality and coincidental associations, and thus increases the understanding of why we observe what we observe. The book contains detailed descriptions of the immune system and the microbial world as well as methodological and conceptual clarifications.

"The book is highly recommended to those who want to dig into the scientific challenges involved in understanding the complex demands and tasks that nature had bestowed the immune system. "

Professor Roland Jonsson

The Gade Institute, University of Bergen, Norway.

 

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Contents

III
1
IV
2
V
14
VI
18
VII
45
VIII
46
IX
65
X
76
XV
117
XVI
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XVII
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XVIII
151
XIX
173
XX
179
XXI
198
XXII
207

XI
81
XII
83
XIII
97
XIV
109
XXIV
209
XXV
211
XXVI
235
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