Determinants of Neuronal Identity
Academic Press, Dec 2, 2012 - Science - 544 pages
Determinants of Neuronal Identity brings together studies of a wide range of vertebrate and invertebrate organisms that highlight the determinants of neuronal identity. Emphasis of this book is on how neurons are generated; how their developmental identities are specified; and to what degree those identities can be subsequently modified to meet the changing needs of the organism. This book also considers various techniques used in the analysis of different organisms.
This volume is comprised of 15 chapters; the first of which introduces the reader to the specification of neuronal identity in Caenorhabditis elegans. The discussion then turns to neurogenesis and segmental homology in the leech, as well as intrinsic and extrinsic factors influencing the development of Retzius neurons in the leech nervous system. Drosophila is discussed next, with particular reference to neuronal diversity in the embryonic central nervous system, cell choice and patterning in the retina, and development of the peripheral nervous system. Other chapters explore endocrine influences on the postembryonic fates of neurons during insect metamorphosis; neuron determination in the nervous system of Hydra and in the mammalian cerebral cortex; and segregation of cell lineage in the vertebrate neural crest.
This book will help scientists and active researchers in synthesizing a conceptual framework for further studies of neuronal specification.
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Chapter 2 Segmental Differentiation of Lineally Homologous Neurons in the Central Nervous System of the Leech
Chapter 3 Control of Central Neurogenesis in the Leech
Chapter 4 Intrinsic and Extrinsic Factors Influencing the Development of Retzius Neurons in the Leech Nervous System
Chapter 5 The Generation of Neuronal Diversity in the Drosophila Embryonic Central Nervous System
Chapter 6 Initial Determination of the Neurectoderm in Drosophila
Chapter 7 Cell Choice and Patterning in the Drosophila Retina
Chapter 8 Development of the Peripheral Nervous System in Drosophila
Chapter 9 Endocrine Influences on the Postembryonic Fates of Identified Neurons during Insect Metamorphosis
Chapter 10 Neuron Determination in the EverChanging Nervous System of Hydra
Chapter 11 Cell Lineage Segregation in the Vertebrate Neural Crest
Chapter 12 The Determination of Neuronal Identity in the Mammalian Cerebral Cortex
Chapter 13 Generation of Neuronal Diversity in the Vertebrate Retina
Chapter 14 Development of Motoneuronal Identity in the Zebrafish
Chapter 15 Cellular and Molecular Mechanisms Determining Neurotransmitter Phenotypes in Sympathetic Neurons
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ablation adult animals antibodies AS-C axons bandlet Biol blast cell body column bristles Campos-Ortega cell death cell division cell fate cell interactions cell lineage cell types cellular central cholinergic clones cluster commitment cone cells cortex cortical cues deﬁned determination developmental dorsal Drosophila melanogaster ecdysteroid ectodermal embryo embryogenesis epidermal expression factors ﬁnal ﬁrst ﬂuorescence formation function ganglia ganglion cells genetic Ghysen Goodman growth cones homologous Horvitz hydra identiﬁed identity inﬂuence innervation insect labeled larval layer leech Manduca migration multipotent muscle mutations Nature London nerve nervous system neural crest cells neuroblast neurogenesis neurogenic genes neurogenic region Neurosci normal Notch ommatidia ommatidial pathway pattern peripheral phenotype pigment cells position posterior precursors primary motoneurons produce progenitor protein retina role Rz neurons segments sense organs sensory neurons sevenless Shankland SMCs speciﬁc subplate subset Sulston sweat glands sympathetic neurons target teloblast tentacle tissue touch cells transplanted wild-type