Developing Brain Behaviour: The Role of Lipids in Infant Formula
Academic Press, Aug 13, 1997 - Medical - 537 pages
Certain long chain polyunsaturated fatty acids (LCPUFAs) are thought to be essential components of the nutrition of infants, including those prematurely born, in the sense that they cannot be synthesises by the immature organism and must therefore be supplied in the diet. Breast milk contains these substances, but many manufactured infant formulae do not.
An absence of dietary LCPUFAs has been thought to affect the development of the brain and retina, possibly leading to abnormalties in cognitive and visual function. Considerable multidisciplinary research has been carried out to investigate this proposition. Diets free from LCPUFAs have been compared with supplemented formulae, or with breast milk.
The conclusions from this research were critically examined by a group of leading paediatricians, nutritionists, experts in visual science and developmental behavioural scientists at a 'Dobbing Workshop' held in the United States in late February, 1997. Each of the Chapters was precirculated to the whole group, commented on before the Workshop, and then exhaustively discussed. The Chapters and Commentaries which are published here have therefore undergone a more extensive peer-review process than is usually the case.
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12 months acid and docosahexaenoic acuity card arachidonic acid assessment Bayley behavioral beneﬁt birth weight brain breast milk breast-fed bronchopulmonary dysplasia Carlson Child Dev Clin Nutr clinical correlations deﬁcits developmental diet dietary docosahexaenoic acid early effects of n-3 eicosapentaenoic acid erythrocyte essential fatty acid factors Fagan Test fatty acid deﬁciency ﬁeld ﬁndings ﬁrst ﬁsh oil formula-fed infants grating acuity growth habituation human infants human milk infant formula infants fed formula inﬂuence Innis intake Jacobson later IQ LCPUFA supplementation levels linoleic acid Lipids look duration maternal McCall measures monkeys months of age n-3 fatty acid n-3 LCPUFA neural Neuringer novelty preference nutrition ot-linolenic acid outcome phospholipid plasma polyunsaturated fatty acids postnatal potential predictive preferential looking preferential looking acuity preterm infants procedure receptor recognition memory reﬂect retinal scores signiﬁcant signiﬁcantly speciﬁc stimulus studies tester tion validity variables versus visual acuity Werkman SH