Development of the Ocular Lens
Frank J. Lovicu, Michael Lee Robinson
Cambridge University Press, Sep 15, 2004 - Medical - 398 pages
This book provides a comprehensive view of research in lens developmental biology, emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that govern lens development has enabled us to understand how the normal lens forms and how developmental processes are involved in the maintenance of its normal structure, function and growth throughout life. This knowledge is fundamental to our understanding of many lens disorders. The ocular lens has also become a model for understanding the developmental biology of more complex organ systems. In this 2004 book, leading experts in lens cell biology and development discuss lens evolution, induction, morphology, the regulation of the lens cell cycle and fiber cell differentiation, as well as lens regeneration. This book is an authoritative treatment of the subject that will serve as a reference for graduate students and research scientists in developmental biology and in the visual sciences, as well as for ophthalmologists.
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Lens Induction and Determination
Transcription Factors in Early Lens Development
Gruss Peter Department of Molecular Cell Biology MaxPlanckInstitute for Biophysical
The Structure of the Vertebrate Lens
Lens Cell Membranes
Lens Cell Cytoskeleton
The Cell Cycle
Role of Matrix and Cell Adhesion Molecules in Lens Differentiation
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Growth Factors in Lens Development
Beebe David Department of Ophthalmology and Visual Science Washington University
Lens Fiber Differentiation
Other editions - View all
actin activity adhesion apoptosis Bassnett Beebe binding Bmp4 cataract Cell Biol cell cycle cell differentiation chick chicken lens complex connexin crystallin gene cultured cyclin cytoplasmic cytoskeleton detected developmental dorsal iris Drosophila ectoderm Eguchi elongating fibers embryonic lens embryos epithelium Eye Res fiber cell differentiation fiber differentiation fibronectin function gap junctions gene expression genetic growth factor growth shells head ectoderm integrin interactions intermediate filament kinase Kuszak lens capsule lens cell differentiation lens development lens epithelial cells lens fiber cells lens induction lens placode lens regeneration lens vesicle lens-specific lenses Lovicu McAvoy membrane Menko microtubules molecular molecules mouse mRNA mutation neural nuclear nucleus Ophthalmol optic vesicle organelles pathways Pax6 PECs phenotype Piatigorsky placode posterior promoter protein Prox1 rat lens receptors region regulation retina role signaling Sox2 specific stage structure studies TGFB tissue Tomarev transcription factors transdifferentiation transgenic transgenic mice ventral iris vertebrate vitro vivo
Page 372 - The PDGF alpha receptor is required for neural crest cell development and for normal patterning of the somites. Development 124: 2691-2700.