Development of the Ocular Lens

Front Cover
Frank J. Lovicu, Michael Lee Robinson
Cambridge University Press, Sep 15, 2004 - Medical - 398 pages
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This book provides a comprehensive view of research in lens developmental biology, emphasising technical and molecular breakthroughs. Elucidation of the mechanisms that govern lens development has enabled us to understand how the normal lens forms and how developmental processes are involved in the maintenance of its normal structure, function and growth throughout life. This knowledge is fundamental to our understanding of many lens disorders. The ocular lens has also become a model for understanding the developmental biology of more complex organ systems. In this 2004 book, leading experts in lens cell biology and development discuss lens evolution, induction, morphology, the regulation of the lens cell cycle and fiber cell differentiation, as well as lens regeneration. This book is an authoritative treatment of the subject that will serve as a reference for graduate students and research scientists in developmental biology and in the visual sciences, as well as for ophthalmologists.
 

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Contents

Lens Induction and Determination
27
Transcription Factors in Early Lens Development
48
Gruss Peter Department of Molecular Cell Biology MaxPlanckInstitute for Biophysical
49
The Structure of the Vertebrate Lens
71
Lens Crystallins
119
Lens Cell Membranes
151
Lens Cell Cytoskeleton
173
The Cell Cycle
191
Role of Matrix and Cell Adhesion Molecules in Lens Differentiation
245
Bassnett Steven Department of Ophthalmology and Visual Science Washington Univer
251
Growth Factors in Lens Development
261
Lens Regeneration
290
Bibliography
313
Beebe David Department of Ophthalmology and Visual Science Washington University
327
Index
387
Copyright

Lens Fiber Differentiation
214

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