Developmental Biology and Cancer
This book addresses possible analogies between cancer and developmental biology. An international group of experts provides a multidisciplinary approach, allowing biological or clinical scientists involved with cancer research to integrate specific information from diverse areas.
Five concepts of cancer are presented, and developmental biology is reviewed at five levels. These are integrated in discussions of failure in organisation as a basis of cancer and its control. The book will be a valuable reference for both newcomers as well as experienced biological and clinical scientists.
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Relative Malignancy and Ontogeny
Epigenetic Nature of Neoplastic Transformation
Patterning and Morphogenesis and the Development
The Role of the Cytoskeleton in the Relationship Between Cell
Genetic Predisposition and Cancer
Invasiveness in Development and Neoplasia
Biology and Mechanisms of Tissue Interactions in Developing
Cell Lineages Fate Determination and Differentiation
Differentiation Therapy of Cancer
Acad activin adhesion molecules angiogenesis antigen basement membrane binding Biochem biological cadherins cancer cells Cancer Res carcinogenesis carcinogenic carcinoma cell adhesion Cell Biol cell lines cell proliferation cell-cell cellular chick chromosome clones culture cytoplasmic developmental Dilman disease ectoderm effects embryo encoding endothelial cells epithelial cells epithelium extracellular matrix fibroblasts formation function gastrulation gene expression gene product genetic gland homeobox hormone human induced inhibition invasion involved leukemia levels lineage malignant mammary mechanisms mesenchyme mesoderm metabolic metastasis metastatic mice molecular morphogenesis mouse embryo mRNA murine mutation Natl neoplasia neoplastic neural crest normal cells oncogenes organization pathways pattern phenotype Proc protein proto-oncogene receptor region regulation regulatory retinoblastoma retinoic acid retinoic acid receptor retinoids role Rubin sarcoma Science sequence signal specific stem cells structures studies therapy tissue transcription factors transgenic translocation tumor cells tumor suppressor genes tumorigenic virus vitro vivo Xenopus