Diagnosis and Management of Multiple Sclerosis
Clinically focused text discusses diagnosis, timing of treatment initiation, and treatment regimen options. Detailed tables on neurologic disorders are provided to assist in differential diagnoses. Guidance is provided on how to best manage initial occurrence of MS and relapses with case study examples. Treatment of symptoms and medical problems that often accompany MS is discussed, along with prognostic indications.
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Abbreviations abnormalities active acute agents antibodies associated ataxia atrophy attacks atypical autoimmune Avonex axonal Betaseron biopsy brain stem CDMS cells cerebral chronic Clin clinical and MRI cognitive Copaxone corticosteroids criteria definite Demos Medical Publishing demyelination differential diagnosis disease course disease-modifying treatment disorders dose drug dysfunction early Ebers GC EDSS effects evaluation evidence Figure follow-up genes genetic glatiramer acetate Goodkin head MRI immune indicated infection interferon Johnson KP lesions magnetic resonance imaging ment mg/d mitoxantrone MRI findings MRI scans multiple scle multiple sclerosis myelin myelopathy neurological neuropathy normal Novantrone oligoclonal bands onset optic neuritis pathology patients periventricular physicians placebo prognosis progressive Rebif Reference regard relapse rate risk RRMS Rudick RA Screening serum significant spasticity specific spinal cord SPMS studies subtype suggestive symptoms syndrome Table testing therapy tients tion tiple tiple sclerosis tive typical usually virus white matter