Diagnosis and Management of Multiple Sclerosis
Clinically focused text discusses diagnosis, timing of treatment initiation, and treatment regimen options. Detailed tables on neurologic disorders are provided to assist in differential diagnoses. Guidance is provided on how to best manage initial occurrence of MS and relapses with case study examples. Treatment of symptoms and medical problems that often accompany MS is discussed, along with prognostic indications.
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Definition and Pathology
Epidemiology and Genetics
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Abbreviations abnormalities active acute antibodies associated ataxia atrophy attacks atypical autoimmune Avonex axonal baclofen Betaseron brain stem cells cerebral chronic Clin clinical and MRI cognitive Copaxone corticosteroids criteria definite Demos Medical Publishing demyelination differential diagnosis disease course disease-modifying treatment disorders dose drug dysfunction Ebers GC EDSS effects evidence Figure follow-up gene genetic glatiramer acetate Goodkin head MRI immune indicated infection interferon Johnson KP lesions magnetic resonance imaging McDonald ment methylprednisolone mg-d mitoxantrone MRI findings MRI scans multiple scle multiple sclerosis myelin myelopathy neuroimaging Neurol Neurosurg Psychiatry neurological neuropathy normal Novantrone oligoclonal bands onset optic neuritis pathology patients periventricular physicians placebo prognosis progressive Rebif relapse rate relapsing-remitting risk RRMS Rudick RA Screening spasticity specific spinal cord SPMS studies subtype suggestive symptoms syndrome Table testing therapy tients tion tiple tiple sclerosis tive typical usually virus white matter