Drug Delivery Research Advances
Drug delivery is a term that refers to the delivery of a pharmaceutical compound to humans or animals. Most common methods of delivery include the preferred non-invasive oral (through the mouth), nasal, pneumonial (inhalation), and rectal routes. Many medications, however, can not be delivered using these routes because they might be susceptible to degradation or are not incorporated efficiently. For this reason many protein and peptide drugs have to be delivered by injection. For example, many immunisations are based on the delivery of protein drugs and are often done by injection. Current efforts in the area of drug delivery include the development of targeted delivery in which the drug is only active in the target area of the body (for example, in cancerous tissues) and sustained release formulations in which the drug is released over a period of time in a controlled manner from a formulation. This new book focuses on worldwide research on drug delivery and targeting at the molecular, cellular, and higher levels.
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CORESHELL POLYMER NANOPARTICLE FORMULATIONS FOR THE ORAL ADMINISTRATION OF PEPTIDES AND PROTEINS
EXCIPIENTS AS MODULATORS OF DRUGCARRIER MEDIATED ABSORPTION IN THE INTESTINE
TASTE MASKING OF UNPLEASANT ORAL DRUGS
MECHANISMS OF DRUG ENTRY INTO NUCLEUS
absorption Acad active agents antigens binding bioadhesion bioavailability biomagnetic BMPs bone tissue Bravo-Osuna Caco-2 cell monolayers carrier Cell Biol Chem chitosan clinical coating collagen colonic concentration copolymers corneal Couvreur Cremophor dendrimers digoxin disintegration dosage forms drug delivery drug delivery systems effect efflux enhanced enterica enzymes epithelial epithelium evaluated excipients expression formulation function gastric gastrointestinal tract gene delivery human immunogenicity implants importin Infect inhibition inhibitors interactions intestinal J.Pharm liposomes magnetic mediated membrane metabolism microemulsions molecular molecules Montanox MRP2 multidrug multidrug resistance nanoparticles Natl NLSs nuclear nucleus ocular drug delivery ocular tissues oral administration P-glycoprotein P-gp particles peptide peptides and proteins permeability Pharm pharmaceutical Pharmacol plasmid PLGA Pluronic polymers prodrugs receptors retinal rhBMP-2 rhodamine rhodamine 123 Salmonella solid dosage forms solubility studies substrate surfactant tablets talinolol targeting taste masking Ther therapeutic therapy thiolated chitosan tight junctions TPGS transport typhi uptake vaccine vector vitro vivo