Drug-Eluting Stents: Advanced Applications for the Management of Coronary Disease

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Christopher J. White
CRC Press, Jun 30, 2005 - Medical - 156 pages
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The cure for restenosis has been the Holy Grail of interventional cardiology since the advent of coronary angioplasty in the late 1970s. The development of stents improved the durability of angioplasty, but in-stent restenosis was a major problem for patients and the physicians. To deliver drugs locally on stents that prevent restenosis is a revolutionary advance. Percutaneous revascularization technology has leaped forward, dramatically altering clinical practices, with what may be the single most important advance in the history of cardiology. There are new delivery platforms and new drugs currently being tested. Despite the continuing advancement, there was a need to collate in a single text, information on drug eluting stents for coronary disease. Chris White and colleagues have put together a logically organized text that progresses from theory to practice, and addresses pharmacologic, technical and strategic issues as they relate to the placement of coronary drug-eluting stents.

 

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Contents

CONTRIBUTORS
7
antiproliferative drugs and
19
Trials of Oral drug therapy to reduce restenosis
33
Clinical trials of bare metal stents to reduce restenosis
57
Broader indications offlabel use for coronary drugeluting stents
81
Complications related to drugeluting stents
95
Patient selection criteria for drugeluting stents
107
Optimal antiplatelet and anticoagulation therapy for
115
Optimal deployment strategies for drugeluting stents
125
Cost analysis for coronary drugeluting stents
137
The future of drugeluting stents
145
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