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12 hours 24 hours absorption acid activity acute Administration and Dosage Adults Adverse Reactions agents amiodarone arrhythmias bioavailability blood pressure breast milk calcium Capsules cardiac Children chronic clearance clinical Contraindications creatinine creatinine clearance daily dose decreased depression diarrhea didanosine digoxin discontinue disease diuretics divided doses Drug Interactions edema effects elderly erythromycin exceed excreted in breast ganciclovir half-life headache heparin hepatic Hypersensitivity hypertension hypokalemia hypotension increased infants infusion inhibitors inhibits initial dose injection intervals Lactation levodopa liver metabolites metabolized mg daily mg once daily mg Rx mg twice daily mg/5 ml mg/day mg/kg mg/kg/day mg/ml ml/min monitor nausea occur pain Parenteral Pharmacokinetics Pharmacology phenytoin potassium Pregnancy propafenone protein quinidine reduce regimen renal function Renal function impairment renal impairment respiratory risk Safety and efficacy severe sodium solution sulfonylureas symptoms syndrome Tablets tachycardia theophylline therapeutic therapy tion toxicity treatment ulcer urinary urine usually Various ventricular vomiting weeks zidovudine