Drugs in Anaesthesia and Intensive Care
In everyday practice, anaesthetists can make use of a wide range of drug treatments, and require readily available and accessible information on the appropriate drugs to use in any given situation. Drugs in Anaesthesia and Intensive Care has quickly established itself as an essential reference text for all anaesthetists, both trainees and consultants. The fourth edition of this book includes information on many new drugs, with information on many others revised. The book describes the pharmacokinetics and pharmodynamics of all the drugs commonly used by anaesthetists, all organized so as to allow rapid access to specific information on the properties and characteristics of almost 200 drugs. Drugs in Anaesthesia and Intensive Care fourth edition successfully provides a comprehensive, up-to-date reference for anaesthetists in training, consultant anaesthetists, intensive care nurses, and anaesthetic assistants.
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absorbed when administered acid activity administered dose administered orally administration/doses The adult adult oral dose Alfentanil anaesthesia analgesia analgesic atracurium bioavailability blood flow blood pressure calcium cardiac output cardiovascular cerebral Chemical clearance co-administered colourless solution concentrations dabigatran decrease Desflurane Distribution The drug dose is excreted drug causes duration of action dysrhythmias Effects CVS elimination half-life Enflurane Etomidate excreted unchanged fentanyl gastrointestinal glucose glucuronide halothane hepatic hydrochloride hypertension hypotension increase infusion inhibits injection containing inotropic intramuscular intravenous isoflurane Kinetics Absorption l/kg leading liver Main action Metabolic/other metabolites mg tablets mg/kg mg/ml minutes ml/min/kg Mode of action morphine muscle myocardial nausea and vomiting neuromuscular blockade nitrous oxide non-depolarizing occur ofthe oxygen peripheral plasma propofol protein protein-bound pulmonary receptors reduced remifentanil removed by haemodialysis renal impairment respiratory depression rocuronium Routes of administration/doses sevoflurane side effects sodium solution for injection Special points sugammadex tion Toxicity/side effects treatment urine vecuronium