Drugs in Anaesthesia and Intensive Care
In everyday practice, anesthesiologists can make use of a wide range of drug treatments, and require readily available and accessible information on the appropriate drug to use in any given situation. The first edition of this book proved an invaluable guide for resident and practicing specialist in instructing them on appropriate drug treatments. This new edition has been fully updated to take into account recent developments in clinical pharmacology, and includes information on many new drugs. The book describes the pharmacokinetics and pharmodynamics of all the drugs commonly used in anesthesia. The improved layout of the book allows rapid access to specific information on the properties and characteristics of 180 different drugs.
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Absorption The drug acid activity adminis administered orally Administration/Doses The adult adult oral dose Alfentanil anaesthesia analgesic arterial bioavailability blockade blood pressure bradycardia calcium cardiac output cardiovascular central nervous system Chemical clearance co-administered colourless solution concentration decrease Desflurane digoxin Distribution The drug dose is excreted drug causes duration of action dysrhythmias Effects CVS elimination half-life Enflurane Etomidate excreted unchanged fentanyl gastric gastrointestinal glucuronide haemodialysis halothane hepatic hydrochloride hypertension hypotension infusion inhibits injection containing inotropic insulin intramuscular intravenous isoflurane Kinetics Absorption leading liver Main Actions Metabolic/Other Metabolism Occurs metabolites mg tablets mg/ml minutes ml/min/kg Mode of Action morphine muscle myocardial nausea and vomiting neuromuscular nitrous oxide oxygen patients peripheral plasma predominantly Presentation produced Propofol protein protein-bound receptors removed by haemodialysis renal impairment respiratory depression Routes of Administration/Doses Sevoflurane side effects solution for injection Special Points suxamethonium systemic vascular resistance thiopentone tion Toxicity/Side Effects treatment urine vasodilation venous ventricular