The Effects of Exercise Training and Acute Exacerbations on Muscle Function in Patients with Chronic Obstructive Pulmonary Disease

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Leuven University Press, 2004 - Medical - 184 pages
This is a Ph.D. dissertation. Chronic obstructive pulmonary disease (COPD) is a disease state characterized by airflow limitation that is not fully reversible. The airflow limitation is usually progressive and associated with an abnormal inflammatory response of the lungs to noxious particles or gases. Clinically, it is characterized by complaints of cough, sputum production, and/or dyspnoea, and diagnosed by a significantly reduced Tiffeneau index. It was the fourth leading cause of death in the United States in 1996, exceeded only by heart attacks, cancers and stroke. Hence, COPD is a major global health problem and its burden on society is growing rapidly. For these reasons, COPD was chosen as a study population in the present project.
 

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Contents

Chapter
2
Muscle force during an acute exacerbation in hospitalised
21
Results
27
Conclusions
33
Expression of inflammatory and anabolic markers in vastus
39
Acute anabolic and inflammatory responses to peak
59
Exercise training during rehabilitation of patients with
75
Resistance versus endurance training in patients with
93
Baseline levels of systemic anabolic and inflammatory
111
Appositions
151
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