Eicosanoids and the Skin

Front Cover
CRC Press, Mar 30, 1990 - Medical - 224 pages
This publication summarizes the increasing knowledge in eicosanoid research. It provides a detailed overview of this rapidly expanding field. The text contains sections on general aspects of arachidonic acid metabolism, the role of eicosanoids in skin diseases, and their biological and biochemical effects in skin. Also included is a section on inhibitors of arachidonic acid metabolism with particular reference to use in dermatology. New concepts covered are: possible physiological role of lipoxygenase products in cutaneous wound healing, restoration and maintenance of cutaneous integrity, and the recently recognized protective function of prostaglandins in skin. It is an invaluable resource for individuals involved with dermatology, pharmacology, inflammation, immunology, biochemistry, physiology, internal medicine and therapeutics.
 

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Contents

Double Dioxygenation Reactions
10
Chapter
11
Arachidonic Acid Metabolism in Normal Skin
23
Chapter 4
45
Chapter 6
67
Chapter 8
91
Chapter 9
107
Chapter 10
127
Effects of Eicosanoids on Human Fibroblast Chemotaxis
149
Chapter 13
171
Chapter 14
185
Chapter 15
204
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