Embryonal Stem Cells: Introducing Planned Changes Into the Animal Germline

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Harwood Academic, 1992 - Science - 147 pages
The Modern Genetics book series will cover a wide range of topics within genetics, including animal, plant, population, evolutionary and molecular genetics. Individual volumes in the series will cover themes such as sex determination, yeast artificial chromosomes and the genetics of toxicology, drug resistance, eye diseases, cancer and psychiatric conditions.
Embryonal Stem Cells: Introducing Planned Changes into the Animal Germline is the first volume in the Modern Genetics book series. Genetic manipulation of embryonal stem cells allows a wide range of precise genetic modifications. The chimaeric animals produced can then transmit these modifications to their offspring. This volume provides an up-to-date review of this rapidly developing area of research, covering embryonal stem cells, homologous recombination and gene targeting, germline transmission of planned genomic modifications and research strategies using genetically modified animals. This volume will be of interest to res

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