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DEFENSINS P S Hiemstra
SIGNAL TRANSDUCTION M Torres and H J Forrnan
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2006 Elsevier Ltd acetylcholine acid activity acute airway alveolar antioxidant apoptosis arterial asbestos associated asthma binding Biology breathing bronchioles cause cellular chemokines chest chronic clinical COPD cough cytokines deﬁned diagnosis disorders domain dyspnea endothelial enzyme epithelial cells exposure expression extracellular ﬁbers ﬁbroblasts ﬁbrosis Figure ﬁndings ﬁrst function gene growth factor hypoxia identiﬁed increased induced infection inﬂammation inﬂammatory inhalation inhibition inhibitors interstitial involved journal kinase lesions levels lung cancer lung disease lung injury macrophages malignant mechanisms mediastinal Medical Medicine membrane mesothelial mesothelial cells mesothelioma mice MMPs Molecular molecules motor neurons mucin mucus myoﬁbroblasts myopathies NADPH oxidase nerve neuromuscular neutrophils normal obstructive occur Overview oxide oxygen oxygen toxicity pathogenesis Pathology pathway patients physiological platelets pleural effusions pleural ﬂuid pneumoconiosis protein pulmonary receptors reduced regulation response result role silicosis smooth muscle speciﬁc studies symptoms syndrome therapy thoracic tion tissue toxic tumor University vascular vitamin