Endocrine Disrupters: Hazard Testing and Assessment Methods

Front Cover
John Wiley & Sons, Feb 4, 2013 - Science - 416 pages
0 Reviews

Enables researchers to assess the effects of endocrine disrupters as well as comply with new environmental regulations

Endocrine disrupters are chemicals—both man-made and natural—that interfere with the body's endocrine system, potentially resulting in adverse developmental, reproductive, neurological, and immune effects. In recent years, a number of regulatory authorities around the world have drafted or enacted legislation that requires the detection and assessment of the effects of endocrine disrupters on both humans and wildlife. In response, this book provides comprehensive, up-to-date information on the latest tested and proven methods used to detect and assess the environmental hazards posed by endocrine-disrupting chemicals.

Endocrine Disrupters is divided into chapters covering each major taxon as well as chapters dedicated to hazard assessment and regulation. The book covers testing methods for all the vertebrate groups and several invertebrate phyla, including:

  • Crustaceans and mollusks
  • Insects
  • Fish
  • Amphibians and reptiles
  • Birds and mammals

Moreover, the book emphasizes practical, ethical testing methods that combine sensitivity, efficiency, statistical power, and reasonable cost.

Each chapter is written by one or more international experts in ecotoxicology, offering readers step-by-step guidance for implementing each method based on the latest research and the authors' firsthand laboratory experience. Furthermore, all the chapters have been subjected to a rigorous peer review and edited in light of the reviewers' comments. References at the end of each chapter guide readers to the literature in the field.

Endocrine Disrupters is recommended for scientists who need to test chemicals for possible endocrine-disrupting properties. It is also recommended for regulatory authorities who need to decide whether particular chemicals can be safely marketed.

 

What people are saying - Write a review

We haven't found any reviews in the usual places.

Contents

Endocrine Disruption in Wildlife
The Regulatory Need for Tests to Detect EDCs
Techniques for Measuring Endocrine Disruption
Crustaceans
REFERENCES
Using Fish to Detect Endocrine Disrupters
Endocrine Disruption and Reptiles
Birds
Mammalian Methods
Ecological Effects of Endocrine Disrupters
The Prospects for Routine Testing
Index
Copyright

Other editions - View all

Common terms and phrases

About the author (2013)

PETER MATTHIESSEN, PhD, is an aquatic ecotoxicologist who works as an independent consultant. Specializing in the study of endocrine disrupters, he has conducted extensive research into how sewage effluents cause feminization in wild male fish as well as how tributyltin-based antifoulants cause masculinization in wild female mollusks. Professor Matthiessen is a member of the UK Advisory Committee on Pesticides and Co-chair of the OECD Validation Management Group for Ecotoxicity Tests. He has contributed to the development of standardized ecotoxicity assays with sensitivity for endocrine disrupters as well as written guidance for the interpretation of the resulting data.

Bibliographic information