Environmental Stressors in Health and Disease

Front Cover
CRC Press, Jul 20, 2001 - Medical - 520 pages
This volume illustrates the impact of environmental oxidants on the tissues of the eyes, lungs and skin, as well as on the immune system - highlighting common illnesses, injuries and pathologies induced by pro-oxidant environmental xenobiotics such as inflammation, immune response, signal transduction, regulation of gene expression, and carcinogene
 

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Contents

1 Free Radical Reactions in Human Disease
1
2 Radicals and Inflammation Mediators and Modulators
17
3 Autoimmunity Caused by Oxidizing Foreign Compounds
53
4 Role of Oxidative Stress in Chemical Carcinogenesis
81
5 Proposed Mechanisms of Arsenic Toxicity Carcinogenesis
103
6 Redox Regulation of Gene Expression and Transcription Factors in Response to Environmental Oxidants
115
7 Cigarette Smoking and Pulmonary Oxidative Damage
135
8 Health Effects of Diesel Exhaust and Diesel Exhaust Particles
157
12 Redox Modulation and Oxidative Stress in Dermatotoxicology
237
13 Dermatotoxicology of Environmental and Occupational Chemical Hazards Agents and Action
271
14 Photooxidative Stress in Skin and Regulation of Gene Expression
319
15 Ozone Stress in the Skin Barrier
335
16 Immunotoxicity of Environmental Agents in the Skin
345
17 Environmental Stressors and the Eye
365
18 Free Radicals and Aging of Anterior Segment Tissues of the Eye
381
19 The Role of Ocular Free Radicals in AgeRelated Macular Degeneration
423

9 The Role of Free Radicals in Asbestos and SilicaInduced Fibrotic Lung Diseases
185
10 Reactive Oxygen Species and SilicaInduced Carcinogenesis
203
11 Atmospheric Oxidants and Respiratory Tract Surfaces
225
20 Nutritional Influences on Risk for Cataract
457
Index
489
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